Tolaz Dt 10mg (15 Tab)

TOLAZ DT 10MG (15 TAB) by TORRENT PHARMACEUTICALS LTD

Name:

• Brand Name: TOLAZ DT 10MG
• Common Name: Olanzapine Dispersible Tablet 10mg

Composition: Each tablet contains Olanzapine 10mg as the active ingredient. Olanzapine is an atypical antipsychotic.

Uses: TOLAZ DT 10MG is primarily used for the management of various psychiatric disorders, including:

• Schizophrenia (to treat symptoms like hallucinations, delusions, and disorganized thinking and behavior).
• Severe manic episodes associated with bipolar I disorder (manic depression) and to prevent their recurrence.
• Agitation in schizophrenia.

Dosage and Administration: This medicine should be taken orally as directed by a healthcare professional. It can be taken with or without food, preferably at the same time each day to maintain a consistent level in the body. Do not discontinue or change the dose without consulting your doctor.

• Schizophrenia: Typically, adults may start with 5 to 10 mg once daily, with dosage adjustments in 5 mg increments at intervals greater than one week.
• Bipolar Mania: Adults may start with 10 to 15 mg once daily, with adjustments in 5 mg increments at intervals greater than 24 hours.
• In debilitated, elderly, or hypotensive-prone adults, a starting dose of 5 mg daily is often recommended.

Side Effects: Common side effects include:

• Drowsiness, dizziness, sleepiness, fatigue
• Weight gain
• Dry mouth, constipation, increased appetite
• Restlessness, tremors/shakiness
• Changes in blood cell levels, increased blood sugar and cholesterol levels

Serious side effects can include an increased risk of death in elderly patients with dementia-related psychosis. Report any involuntary face, tongue, mouth, or lip movements (tardive dyskinesia) to your doctor.

Precautions:

• Elderly Patients: Use with caution in elderly patients; it is not recommended for those with dementia-related psychosis due to increased risk of death.
• Pregnancy and Breastfeeding: Consult your doctor. Tolaz DT 10MG may be unsafe during pregnancy and is not recommended during breastfeeding.
• Alcohol: Avoid alcohol consumption as it can increase drowsiness and other side effects.
• Driving: Avoid driving or operating heavy machinery until you know how the medicine affects you, as it can cause dizziness and sleepiness.
• Medical Conditions: Inform your doctor if you have a history of blood clotting, stroke, Parkinson's disease, heart, liver, or kidney disease, diabetes, glaucoma, or seizures.
• Interactions: Olanzapine may interact with antihypertensive drugs, carbamazepine, fluvoxamine, sedating drugs, alcohol, levodopa, and other dopamine agonists. Avoid grapefruit or grapefruit juice.

Storage: Store in a cool and dry place, away from sunlight and moisture. Keep it out of the sight and reach of children. Disintegrating tablets should be handled with dry hands after peeling back the foil.

What is TOLAZ DT 10MG used for?

TOLAZ DT 10MG, which contains the active ingredient Olanzapine, is primarily used to treat schizophrenia and acute manic episodes associated with bipolar I disorder. It can also be used to manage agitation in schizophrenia and, in some cases, in combination with other medications for depression.

How does TOLAZ DT 10MG work?

TOLAZ DT 10MG is an atypical antipsychotic medication. It works by balancing the levels of certain chemical messengers in the brain, specifically dopamine and serotonin. By affecting these neurotransmitters, it helps to improve mood, thoughts, and behavior, reducing symptoms like hallucinations, delusions, and mood swings.

What is the usual dosage of TOLAZ DT 10MG?

The usual dosage varies depending on the condition being treated. For schizophrenia, treatment typically starts with 5 to 10 mg once daily. For acute manic episodes of bipolar I disorder, a starting dose of 10 to 15 mg once daily is common. Your doctor will adjust the dose in small increments based on your response. It should be taken once daily, with or without food, preferably at the same time each day to maintain consistent medicine levels.

What are the possible side effects of TOLAZ DT 10MG?

Common side effects include drowsiness, dizziness, weight gain, dry mouth, constipation, increased appetite, and restlessness. Some individuals may also experience tremors, fatigue, swelling of the hands or feet, and increased prolactin levels in the blood. More serious, though less common, side effects can include tardive dyskinesia (involuntary movements), orthostatic hypotension (sudden drop in blood pressure upon standing), increased blood sugar and cholesterol levels, and blood clots.

Is TOLAZ DT 10MG safe during pregnancy or breastfeeding?

TOLAZ DT 10MG is generally not recommended during pregnancy (Pregnancy Category C) unless the potential benefits outweigh the risks. Using it during the last three months of pregnancy may cause unwanted symptoms in the newborn, such as shaking, muscle stiffness, sleepiness, or breathing problems. It is also not recommended for breastfeeding mothers as the medication can pass into breast milk and may harm the baby. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can TOLAZ DT 10MG be taken with other medications?

TOLAZ DT 10MG can interact with various medications. For example, it may enhance the hypotensive effects of antihypertensive drugs, and its levels can be affected by medications like Carbamazepine (which can lower olanzapine levels) and Fluvoxamine (which can elevate olanzapine levels). Taking it with sedating drugs or alcohol can lead to additive central nervous system (CNS) depression. Olanzapine may also antagonize the effects of levodopa and other dopamine agonists. It is crucial to inform your doctor about all prescription, over-the-counter, and herbal medications you are taking. Avoid grapefruit and grapefruit juice as they can affect how the medicine works.

What precautions should be taken while taking TOLAZ DT 10MG?

Several precautions should be observed:

• Elderly patients with dementia-related psychosis should generally avoid this medication due to an increased risk of death.
• Monitor blood sugar, cholesterol, and weight regularly, as this medication can cause increases in these levels.
• Use with caution if you have heart disease, liver or kidney disease, diabetes, glaucoma, a history of seizures, or conditions that predispose to low blood pressure.
• Avoid alcohol and other CNS depressants, as they can increase drowsiness and dizziness.
• Do not drive or operate heavy machinery until you know how the medication affects you, as it can cause drowsiness and dizziness.
• Rise slowly from a sitting or lying position to prevent orthostatic hypotension.
• Do not stop taking the medication suddenly without consulting your doctor, as abrupt discontinuation can lead to unpleasant withdrawal symptoms like sweating, tremor, anxiety, nausea, and vomiting. Your doctor will advise on gradual tapering.
• Report any unusual movements of the face or tongue to your doctor, as these could be signs of tardive dyskinesia.
• Avoid becoming overheated.

What happens if a dose of TOLAZ DT 10MG is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should TOLAZ DT 10MG be stored?

TOLAZ DT 10MG should be stored at room temperature, ideally below 30°C (or between 10ºC to 25ºC). Keep it in a tightly closed container and protect it from light and moisture. Ensure it is kept out of the reach of children and pets.