Thyrox 125 Mcg Tablet (120 Tab)

THYROX 125 MCG TABLET (120 TAB) by MACLEODS PHARMACEUTICALS LTD.

• Name:

  • Brand Name: THYROX 125 MCG TABLET
  • Common Name: Levothyroxine Sodium (Thyroxine Sodium)

• Composition:

  • Each tablet contains 125 micrograms of Thyroxine Sodium (Levothyroxine sodium), a synthetic form of the thyroid hormone T4.

• Uses: THYROX 125 MCG TABLET is primarily used for:

  • Treatment of hypothyroidism (underactive thyroid gland), a condition where the thyroid gland does not produce sufficient thyroid hormones.
  • Management of goitre (enlarged thyroid gland).
  • Hormone replacement therapy after surgical removal of the thyroid gland.
  • Suppression of thyroid-stimulating hormone (TSH) in certain types of thyroid cancer.

• Dosage and Administration:

  • Thyrox 125 Tablet should be taken orally on an empty stomach, ideally first thing in the morning, at least 30-60 minutes before breakfast, tea, or coffee.
  • Swallow the tablet whole with a glass of water.
  • The dose and duration are determined by a healthcare professional based on individual thyroid hormone levels and medical condition. Regular blood tests are necessary to monitor effectiveness and adjust the dose.

• Side Effects: Common side effects may include:

  • Headache
  • Diarrhoea, abdominal cramps, nausea, vomiting
  • Weight loss, increased appetite
  • Nervousness, irritability, sleeplessness (insomnia)
  • Excessive sweating, feeling hot even in cool environments, heat intolerance
  • Muscle cramps, muscle weakness, tremors (shaking of hands)
  • Palpitations (irregular heartbeat), chest pain
  • Changes in menstrual cycle Serious side effects, though less common, can include severe allergic reactions.

• Precautions:

  • Inform your doctor if you have allergies to any components, heart conditions (e.g., angina, acute myocardial infarction, hypertension), diabetes, hyperthyroidism, thyrotoxicosis, or adrenal insufficiency.
  • Thyrox 125 Tablet may affect blood sugar levels, requiring dose adjustments for diabetic patients.
  • Long-term use, especially in post-menopausal women, may reduce bone mineral density.
  • Consult your doctor if you are pregnant or breastfeeding, as dosage requirements may change.
  • Avoid taking antacids, calcium or iron supplements, and multivitamins within at least 4 hours of taking Thyrox 125 Tablet, as they can interfere with absorption. Certain foods like soy products, cabbage, and cauliflower may also affect absorption; consult your doctor regarding dietary interactions.
  • Do not discontinue or alter the dosage without consulting your doctor.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC. Keep in the original container.

THYROX 125 MCG TABLET (120 TAB) by MACLEODS PHARMACEUTICALS LTD. is a medication containing levothyroxine sodium, a synthetic thyroid hormone. It is prescribed for conditions where the thyroid gland does not produce enough of its own hormones.

What is THYROX 125 MCG TABLET used for?

THYROX 125 MCG TABLET is primarily used to treat hypothyroidism, a condition where the thyroid gland is underactive and does not produce sufficient thyroid hormones. It is also used as replacement therapy after the thyroid gland has been surgically removed, to manage enlarged thyroid glands (goitre), and as an adjunct to surgery and radioactive iodine therapy for certain types of thyroid cancer.

How does THYROX 125 MCG TABLET work?

This medicine contains levothyroxine, which is a synthetic version of thyroxine (T4), a hormone naturally produced by your thyroid gland. It works by replacing the missing thyroid hormone in your body, helping to restore normal energy levels, regulate metabolism, and alleviate symptoms associated with an underactive thyroid. Levothyroxine (T4) is a prohormone that is converted into its active form, triiodothyronine (T3), within the body, which then influences various metabolic processes.

What is the usual dosage for THYROX 125 MCG TABLET?

The dosage of THYROX 125 MCG TABLET is individualized by your doctor based on your specific condition, age, and regular blood tests (especially Thyroid Stimulating Hormone or TSH levels). It is typically taken once daily in the morning, ideally at least 30 to 60 minutes before breakfast or any other medications, with a glass of water, on an empty stomach.

What are the possible side effects of THYROX 125 MCG TABLET?

Most side effects occur if the dose is too high. Common side effects can include rapid or irregular heartbeats (palpitations), chest pain, nervousness, irritability, sleeplessness, tremors, headache, increased sweating, heat intolerance, changes in appetite, weight loss or gain, diarrhea, and temporary hair loss. Serious side effects are rare but may include allergic reactions like skin rash, swelling of the face or throat, or difficulty breathing, which require immediate medical attention. Long-term use of high doses can also lead to bone loss (osteoporosis), especially in post-menopausal women.

Is THYROX 125 MCG TABLET safe during pregnancy or breastfeeding?

Yes, THYROX 125 MCG TABLET is generally considered safe during both pregnancy and breastfeeding. It is crucial to continue taking this medication throughout pregnancy, as untreated hypothyroidism can lead to complications for both the mother and the baby. Your doctor will likely need to adjust your dose and monitor your thyroid levels regularly during pregnancy. During breastfeeding, only minimal amounts of thyroid hormones pass into breast milk, which are too small to harm the baby. Maintaining proper thyroid hormone levels in the mother is important for her health and adequate milk production.

Can THYROX 125 MCG TABLET be taken with other medications?

Many medications, supplements, and certain foods can interact with THYROX 125 MCG TABLET and affect its absorption or effectiveness. It is important to inform your doctor or pharmacist about all prescription and non-prescription medicines, vitamins, nutritional supplements, and herbal products you are taking. Medications like antacids, calcium or iron supplements, proton pump inhibitors, and certain cholesterol-lowering drugs should typically be taken at least 4 hours apart from THYROX 125 MCG TABLET to prevent reduced absorption. Other drugs such as epilepsy medicines, rifampicin, amiodarone, oestrogens, warfarin, and diabetes medications may require dose adjustments when taken concurrently. Foods like grapefruit, coffee, soy products, walnuts, and dietary fiber can also interfere with absorption.

What precautions should be taken while using THYROX 125 MCG TABLET?

Take this medicine exactly as prescribed by your doctor; do not change your dose or stop taking it without medical advice. Regular blood tests are necessary to monitor your thyroid hormone levels. This medication should not be used for weight loss or to treat obesity. Inform your doctor if you have pre-existing heart conditions, diabetes (as it may affect blood sugar levels), adrenal insufficiency, thyrotoxicosis, or thyroid nodules. Always inform any doctor, dentist, or pharmacist treating you that you are taking THYROX. Avoid switching between different brands of levothyroxine without your doctor's approval.

What happens if a dose of THYROX 125 MCG TABLET is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose (e.g., more than 3 hours have passed). In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Due to levothyroxine's long half-life, a single missed dose is unlikely to significantly impact your thyroid hormone levels. If you frequently miss doses or miss several doses in a row, consult your doctor.

How should THYROX 125 MCG TABLET be stored?

Store THYROX 125 MCG TABLET below 25°C. Keep the tablets in their original bottle, tightly closed, and protect them from light, moisture, and heat. Do not use the tablets if their color has changed. Always keep this medicine out of the sight and reach of children.