Sitalembic 100 Mg Tablet (15 Tab)

SITALEMBIC 100 MG TABLET (15 TAB) by ALEMBIC PHARMACEUTICALS LIMITED

Name

• Common Name: Sitagliptin 100mg
• Brand Name: Sitalembic 100 Tablet

Composition

Sitalembic 100 Tablet contains Sitagliptin 100 mg as its active ingredient. It belongs to a class of medications known as Dipeptidyl Peptidase-4 (DPP-4) inhibitors.

Uses

Sitalembic 100 Tablet is primarily used for the management of Type 2 Diabetes Mellitus in adults. It works by improving the body's ability to lower blood sugar levels, particularly after meals, by increasing insulin production and reducing glucose production by the liver. It is often prescribed alongside a healthy diet and regular exercise, and can be used alone or in combination with other anti-diabetic medications to achieve better blood sugar control and prevent serious long-term complications such as kidney damage, eye problems (retinopathy), nerve issues (neuropathy), and an increased risk of heart attack or stroke.

Dosage and Administration

The typical recommended dosage for Sitalembic 100 Tablet for adults is 100mg once daily. It can be taken with or without food. The tablet should be swallowed whole with a glass of water; it should not be crushed, chewed, or split. For optimal results, it is advisable to take the tablet at the same time each day. Your doctor may adjust the dosage based on your condition and blood sugar levels. Do not discontinue the medication without consulting your doctor.

Side Effects

While Sitalembic 100 Tablet is generally well-tolerated, some common side effects may include:

• Headache
• Upper respiratory tract infections (such as nasopharyngitis or common cold)
• Sore throat
• Nausea
• Diarrhea
• Stomach discomfort or pain
• Skin rash and itching

More serious but less common side effects can include:

• Low blood sugar (hypoglycemia), especially when used in combination with other diabetes medications like insulin or sulfonylureas.
• Inflammation of the pancreas (pancreatitis), which can be severe.
• Severe allergic reactions such as anaphylaxis, angioedema, or skin conditions like Stevens-Johnson syndrome.
• Kidney-related issues, particularly in individuals with pre-existing kidney conditions.
• Heart failure.
• Joint pain. Seek immediate medical attention if you experience severe abdominal pain or any signs of a serious allergic reaction.

Precautions

• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Sitalembic 100 Tablet during pregnancy is not well-established, and it is probably unsafe during breastfeeding.
• Kidney/Liver Impairment: Patients with moderate to severe kidney impairment may require dose adjustments due to reduced clearance of the medication. It is generally considered safe for patients with liver disease if prescribed by a doctor.
• Alcohol: Avoid alcohol consumption while taking this medicine, as it can interfere with blood sugar control and increase the risk of side effects like dizziness and drowsiness.
• Driving and Operating Machinery: Use caution when driving or operating machinery if you experience dizziness or symptoms of low blood sugar.
• Drug Interactions: Inform your doctor about all other medications you are taking, as Sitalembic 100 Tablet can interact with insulin, sulfonylureas (increasing the risk of hypoglycemia), certain cationic medicines (e.g., cimetidine), and carbonic anhydrase inhibitors.
• Pre-existing Medical Conditions: Inform your doctor if you have a history of pancreatitis, gallstones, high levels of fat in the blood, Type 1 diabetes, or diabetic ketoacidosis. This medication is not suitable for Type 1 diabetes or diabetic ketoacidosis.
• Pediatric Use: Sitalembic 100 Tablet is not recommended for children below 18 years of age.
• Elderly Patients: Use with caution in elderly patients. Regular monitoring of blood sugar levels is crucial during treatment.

Storage

Store Sitalembic 100 Tablet in a cool, dry place, ideally below 30°C (some sources specify below 25°C), away from direct sunlight and moisture. Keep it out of sight and reach of children. Do not use the medicine past its expiry date.

What is SITALEMBIC 100 MG TABLET used for?

SITALEMBIC 100 MG TABLET is an oral medication primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed alongside a healthy diet and regular exercise to improve glycemic control. It can be used alone or in combination with other diabetes medications like metformin or insulin. This medication helps prevent serious long-term complications associated with diabetes, such as kidney damage, nerve problems, and blindness.

How does SITALEMBIC 100 MG TABLET work?

SITALEMBIC 100 MG TABLET contains Sitagliptin, which belongs to a class of drugs called DPP-4 (dipeptidyl peptidase-4) inhibitors. It works by blocking the action of the DPP-4 enzyme, which normally breaks down certain hormones called incretins. By inhibiting DPP-4, Sitagliptin increases the levels of these incretin hormones, which then stimulate the pancreas to produce more insulin after meals and reduce the amount of glucose released by the liver. This helps to lower overall blood sugar levels.

What is the usual dosage of SITALEMBIC 100 MG TABLET?

The typical recommended dose of SITALEMBIC 100 MG TABLET for adults is 100 mg once daily. It can be taken with or without food. It is important to swallow the tablet whole with a glass of water and not to crush or chew it. For best results, it is advised to take the tablet at the same time each day. Your doctor may adjust the dose based on your specific condition and blood sugar levels.

What are the possible side effects of SITALEMBIC 100 MG TABLET?

Common side effects of SITALEMBIC 100 MG TABLET may include headache, upper respiratory tract infections (like a common cold or sore throat), nasopharyngitis (inflammation of the nasal passages), and diarrhea or stomach discomfort. While SITALEMBIC 100 MG TABLET is less likely to cause low blood sugar (hypoglycemia) when used alone, it can occur, especially if taken with other diabetes medications like insulin or sulfonylureas. Serious but rare side effects can include pancreatitis (inflammation of the pancreas) and allergic reactions. If you experience severe abdominal pain, severe allergic reactions, or symptoms of low blood sugar, seek immediate medical attention.

Is SITALEMBIC 100 MG TABLET safe during pregnancy or breastfeeding?

The safety of SITALEMBIC 100 MG TABLET during pregnancy and breastfeeding is not well-established. Caution is advised, and it is crucial to consult your doctor to assess the potential risks and benefits if you are pregnant, planning to become pregnant, or breastfeeding. It is generally contraindicated during breastfeeding unless considered necessary by your doctor.

Can SITALEMBIC 100 MG TABLET be taken with other medications?

Yes, SITALEMBIC 100 MG TABLET can be prescribed with other diabetes medications such as metformin or insulin to improve blood sugar control. However, combining it with insulin or other oral hypoglycemics (like sulfonylureas) may increase the risk of hypoglycemia (low blood sugar), requiring close monitoring of blood glucose levels and potential dose adjustments. It is not recommended to combine SITALEMBIC 100 MG TABLET with other DPP-4 inhibitors. Inform your doctor about all other medications, including supplements and herbal products, you are currently taking to avoid potential interactions.

What precautions should be taken while using SITALEMBIC 100 MG TABLET?

Before taking SITALEMBIC 100 MG TABLET, inform your doctor if you have a history of kidney disease (dose adjustment may be needed for moderate to severe impairment), pancreas problems (like pancreatitis or gallstones), heart issues (including heart failure), or if you consume alcohol frequently. Avoid or limit alcohol consumption as it can increase the risk of low blood sugar. If you experience dizziness or hypoglycemia, avoid driving or operating machinery. Regular check-ups, including kidney function and blood glucose level monitoring, are important. This medication is not recommended for children under 18 years of age.

What happens if a dose of SITALEMBIC 100 MG TABLET is missed?

If you miss a dose of SITALEMBIC 100 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SITALEMBIC 100 MG TABLET be stored?

SITALEMBIC 100 MG TABLET should be stored in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC. Do not use the medicine past its expiry date.