Glimisave Dm 1/1000mg Tab

GLIMISAVE DM 1/1000MG Tablet

GLIMISAVE DM 1/1000MG Tablet is an antidiabetic medication manufactured by Eris Therapeutics Limited.

Composition Each tablet contains a combination of three active ingredients:

• Dapagliflozin: 10 mg (a sodium-glucose cotransporter-2 inhibitor)
• Glimepiride: 1 mg (a sulfonylurea)
• Metformin: 1000 mg (a biguanide)

These components work synergistically to lower blood sugar levels through various mechanisms. Dapagliflozin helps remove excess sugar from the body via urine. Glimepiride stimulates the pancreas to produce more insulin, while Metformin reduces glucose production by the liver, delays glucose absorption from the intestines, and improves insulin sensitivity.

Uses GLIMISAVE DM 1/1000MG Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is particularly indicated when lifestyle changes, such as diet and exercise, or treatment with a single or dual therapy, are insufficient to achieve adequate glycemic control. This medication aids in controlling high blood sugar levels, improving glycemic control, and can help prevent or delay diabetes-related complications like kidney damage, eye damage, nerve problems, and may reduce the risk of heart attack or stroke in patients with type 2 diabetes.

Dosage and Administration The tablet should be taken orally as directed by a healthcare professional. It can be taken with or without food, but it is often advised to take it consistently at the same time each day, usually once daily, to minimize stomach upset and help prevent low blood sugar episodes. The tablet should be swallowed whole with water and not crushed, cut, or chewed. Dosage will be determined by the doctor based on individual blood sugar levels, response to treatment, and kidney function.

Side Effects Common side effects may include:

• Vomiting, nausea, abdominal pain, diarrhea, loss of appetite
• Headache, dizziness, asthenia (weakness)
• Allergic reactions, female genital infections, urinary tract infections
• Hypoglycemia (low blood sugar), sore throat, muscle pain, back pain, increased urination

Serious side effects, though rare, can include lactic acidosis (a life-threatening buildup of lactic acid in the blood). Patients should seek immediate medical attention if serious symptoms occur or common side effects persist or worsen.

Precautions

• Contraindications: GLIMISAVE DM 1/1000MG Tablet should not be used in individuals with Type 1 diabetes mellitus, diabetic ketoacidosis, severe kidney disease (eGFR below 30 ml/min/1.73 m²), severe liver disease, bladder cancer, severe heart failure, severe low blood pressure, severe dehydration, or known allergy to any of its components.
• Alcohol: Avoid consuming alcohol as it increases the risk of hypoglycemia and lactic acidosis.
• Pregnancy and Breastfeeding: It is generally not recommended during the second and third trimesters of pregnancy and is contraindicated during breastfeeding. Consult a doctor if pregnant or breastfeeding.
• Driving: Patients should be cautious while driving or operating machinery as the medicine may cause low blood sugar, affecting concentration and reaction time.
• Interactions: Inform your doctor about all medicines, supplements, or herbal products being taken to avoid potential interactions. Particular care is needed with insulin secretagogues, highly protein-bound medicines (e.g., salicylates, sulfonamides, chloramphenicol), carbonic anhydrase inhibitors (e.g., acetazolamide, topiramate), diuretics (e.g., furosemide, hydrochlorothiazide), iodinated contrast agents, and certain medications for tuberculosis, high cholesterol, and pain/fever.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is recommended during therapy. Maintaining good hygiene can help prevent genital fungal infections.

Storage Store GLIMISAVE DM 1/1000MG Tablet in a cool and dry place, away from direct sunlight. It should be kept at temperatures between 10ºC and 25ºC or below 30ºC, and out of the sight and reach of children.

GLIMISAVE DM 1/1000MG TAB is an antidiabetic medication commonly used to manage Type 2 Diabetes Mellitus. It combines three active ingredients to help control blood sugar levels.

What is GLIMISAVE DM 1/1000MG TAB used for?

GLIMISAVE DM 1/1000MG TAB is used to treat Type 2 Diabetes Mellitus in adults. It helps manage high blood sugar levels when diet, exercise, and other single or dual therapies are not sufficient. This medication aims to improve glycemic control and reduce HbA1c levels.

How does GLIMISAVE DM 1/1000MG TAB work?

This medication is a combination of three active ingredients: Dapagliflozin, Glimepiride, and Metformin. Dapagliflozin works by increasing the removal of excess sugar from the body through urine. Glimepiride stimulates the pancreas to produce more insulin and enhances the body's response to insulin. Metformin helps reduce glucose production in the liver and decreases sugar absorption from the intestines, while also improving the body's sensitivity to insulin.

What is the usual dosage for GLIMISAVE DM 1/1000MG TAB?

The dosage of GLIMISAVE DM 1/1000MG TAB is determined by your doctor based on your blood sugar levels, response to treatment, and any other medications you may be taking. It should be taken exactly as prescribed, typically once daily, with or without food, preferably with the first meal of the day. It is crucial not to exceed the recommended dose.

What are the possible side effects of GLIMISAVE DM 1/1000MG TAB?

Common side effects may include low blood sugar levels (hypoglycemia), nausea, vomiting, abdominal pain, headache, dizziness, asthenia (weakness), diarrhea, constipation, sore throat, muscle pain, genital fungal infections, and increased urination. Serious but rare side effects can include lactic acidosis and severe urinary tract infections. If any side effects persist or worsen, consult your doctor.

Is GLIMISAVE DM 1/1000MG TAB safe during pregnancy or breastfeeding?

GLIMISAVE DM 1/1000MG TAB is generally not recommended during pregnancy, especially in the second and third trimesters, as it may negatively affect kidney development in the unborn baby. It is also generally not recommended or contraindicated during breastfeeding, as its active ingredients can pass into breast milk and may cause low blood sugar in nursing infants. Always inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can GLIMISAVE DM 1/1000MG TAB be taken with other medications?

GLIMISAVE DM 1/1000MG TAB can interact with other medications. It is important to inform your doctor about all medicines, supplements, and herbal products you are currently taking. Specific interactions to be aware of include those with diuretics (which may increase the risk of dehydration and low blood pressure), insulin and other insulin secretagogues (which can lead to extremely low blood sugar levels), protein-bound medicines (like salicylates, sulfonamides, and chloramphenicol), and carbonic anhydrase inhibitors (which may increase the risk of lactic acidosis).

What precautions should be taken while taking GLIMISAVE DM 1/1000MG TAB?

Avoid this medication if you are allergic to any of its components. It is not recommended for individuals with Type 1 diabetes or children under 18 years of age. Inform your doctor about any history of kidney or liver disease, heart problems, hypertension, urinary tract infections, severe heart failure, bladder cancer, diabetic ketoacidosis, severe low blood pressure, or severe dehydration. Alcohol consumption should be avoided as it increases the risk of hypoglycemia and lactic acidosis. Regular monitoring of blood sugar levels and kidney function is advised. Stay well-hydrated and be cautious while driving or operating machinery, as your blood sugar levels can affect concentration.

What happens if a dose of GLIMISAVE DM 1/1000MG TAB is missed?

If you miss a dose of GLIMISAVE DM 1/1000MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should GLIMISAVE DM 1/1000MG TAB be stored?

Store GLIMISAVE DM 1/1000MG TAB in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children and pets. The medicine should be stored at temperatures below 30°C.