Oxramet S Xr 1000 Mg Tablet (7 Tab)

OXRAMET S XR 1000 MG TABLET

Name:

• Brand Name: OXRAMET S XR 1000 MG TABLET
• Manufacturer: SUN PHARMA LABORATORIES LTD.

Composition: Each extended-release tablet contains a combination of three active ingredients:

• Dapagliflozin: 10 mg
• Metformin Hydrochloride: 1000 mg
• Sitagliptin: 100 mg

Uses: OXRAMET S XR 1000 MG TABLET is prescribed for the effective management of Type 2 Diabetes Mellitus in adults. It works to:

• Lower blood sugar levels
• Improve insulin sensitivity
• Aid in weight management (as advised by a doctor)
• Reduce the risk of heart disease and provide cardiovascular protection
• Provide kidney protection
• Induce ovulation in Polycystic Ovary Syndrome (PCOS) in specific circumstances

Dosage and Administration: This medicine should be taken orally as directed by a healthcare professional.

• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• It can be taken with or without food, but it is generally recommended to take it at the same time each day for optimal benefits and to minimize gastrointestinal side effects.
• The dosage is individualized based on blood glucose levels and treatment response. Do not exceed the prescribed dose or stop the medication without consulting your doctor.

Side Effects: Patients may experience side effects, which can range from common to serious.

• Common Side Effects: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, constipation, fatigue, increased urination, back pain, genital mycotic (fungal) infections, urinary tract infections, nasopharyngitis (common cold symptoms), and upper respiratory tract infections.
• Serious Side Effects: Hypoglycemia (low blood sugar), lactic acidosis (symptoms include rapid breathing, stomach pain, muscle cramps, severe tiredness), allergic reactions (rash, itching, swelling of face/tongue/lips), and liver problems (yellowing of skin/eyes). Seek immediate medical attention if serious side effects occur.

Precautions:

• Contraindications: Do not use if allergic to any components, or in patients with severe renal impairment (including dialysis), severe liver disease, type 1 diabetes, diabetic ketoacidosis, severe dehydration, or uncontrolled diabetes.
• Pregnancy and Breastfeeding: Not recommended during pregnancy, especially in the second and third trimesters, and generally not advised for breastfeeding women. Consult a doctor.
• Alcohol: Avoid excessive alcohol consumption as it increases the risk of lactic acidosis and hypoglycemia.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbal products being taken. Interactions can occur with diuretics, insulin, sulfonylureas, and carbonic anhydrase inhibitors, potentially affecting blood sugar levels or increasing the risk of side effects.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is recommended.
• Pediatric Use: Not recommended for use in children below 18 years of age.
• Elderly Patients: Use with caution in older patients, as they may have underlying liver and kidney issues.

Storage: Store OXRAMET S XR 1000 MG TABLET in a cool and dry place, away from heat, moisture, and direct sunlight. Keep it out of reach of children and pets. Store at or below 30°C.

OXRAMET S XR 1000 MG TABLET is a medication used to treat Type 2 Diabetes Mellitus. It contains a combination of three active ingredients: Dapagliflozin, Metformin, and Sitagliptin.

What is OXRAMET S XR 1000 MG TABLET used for?

OXRAMET S XR 1000 MG TABLET is primarily used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus, especially when blood sugar is not adequately controlled by diet, exercise, or other single antidiabetic medicines alone. It also offers benefits in reducing the risk of heart failure and diabetic kidney disease.

How does OXRAMET S XR 1000 MG TABLET work?

This medicine works through the combined action of its three ingredients:

• Dapagliflozin: This acts as a sodium-glucose cotransporter 2 (SGLT2) inhibitor, increasing the removal of excess sugar from the body through urine.
• Metformin: This biguanide reduces glucose production by the liver cells and delays sugar absorption from the intestines. It also improves the body's sensitivity to insulin.
• Sitagliptin: This works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

What is the usual dosage of OXRAMET S XR 1000 MG TABLET?

The usual dosage is typically one tablet once daily, as advised by your doctor. It should be swallowed whole with a glass of water, without crushing or chewing, and can be taken with food to minimize stomach upset. It's important not to exceed the prescribed dose.

What are the possible side effects of OXRAMET S XR 1000 MG TABLET?

Common side effects may include vomiting, nausea, abdominal pain, headache, stomach upset, urinary tract infections, genital fungal infections, nasopharyngitis (common cold symptoms), upper respiratory tract infections, and diarrhea. More serious but less common side effects can include lactic acidosis (symptoms like rapid breathing, stomach pain, muscle cramps), hypoglycemia (low blood sugar), allergic reactions, and liver problems. If any side effects persist or worsen, consult your doctor.

Is OXRAMET S XR 1000 MG TABLET safe during pregnancy or breastfeeding?

OXRAMET S XR 1000 MG TABLET is generally not recommended during pregnancy or breastfeeding due to limited safety information. It is crucial to inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before taking this medicine.

Can OXRAMET S XR 1000 MG TABLET be taken with other medications?

This medicine can interact with other medications. Particular care should be taken if you are also taking diuretics (which can increase the risk of dehydration and low blood pressure), insulin or insulin secretagogues (like sulfonylureas, which may increase the risk of very low blood sugar levels), or carbonic anhydrase inhibitors (which might raise the risk of lactic acidosis). Always inform your doctor about all other medicines, herbal products, and supplements you are taking to avoid potential interactions.

What precautions should be taken while using OXRAMET S XR 1000 MG TABLET?

Precautions include informing your doctor about any pre-existing kidney or liver issues, a history of pancreatitis, or urinary tract infections. Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis. Temporary discontinuation may be necessary before surgery or imaging procedures involving contrast dyes. This medicine is not recommended for use in children below 18 years of age.

What happens if a dose of OXRAMET S XR 1000 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should OXRAMET S XR 1000 MG TABLET be stored?

Store OXRAMET S XR 1000 MG TABLET in a cool and dry place, away from direct sunlight and moisture. The storage temperature should be below 30°C. Keep it out of the sight and reach of children and pets.