Nebistar 10 Mg Tablet (15 Tab)

NEBISTAR 10 MG TABLET

NEBISTAR 10 MG TABLET is a medication manufactured by Lupin Ltd.

• Composition: Each tablet contains Nebivolol (10mg) as its active ingredient.

• Uses: This medicine is primarily used to treat high blood pressure (hypertension), helping to lower blood pressure and reduce the risk of associated complications like heart attacks and strokes. It is also prescribed for the management of mild to moderate chronic heart failure in patients aged 70 years and older, in conjunction with other therapies. Additionally, it can alleviate symptoms caused by an overactive thyroid gland and is used for migraine prevention.

• Dosage and Administration: Nebistar 10 Tablet is taken orally, with or without food, preferably at the same time each day to maintain consistent blood levels. For hypertension, the usual initial dose is often 5 mg once daily, which may be gradually increased by a doctor. For stable chronic heart failure in elderly patients, treatment typically begins with a low dose (e.g., 1.25 mg once daily) and is gradually increased under medical supervision. Do not discontinue the medication abruptly, as this can lead to a sudden increase in blood pressure.

• Side Effects: Common side effects include headache, dizziness, fatigue, nausea, shortness of breath, edema (swelling), low blood pressure, constipation, and diarrhea. Some individuals may experience a slow heart rate (bradycardia). Serious side effects, though rare, can include severe allergic reactions with rash, swelling, or breathing difficulties.

• Precautions: Inform your doctor about any existing liver or kidney problems, heart conditions (such as a very slow heartbeat, severe heart failure, or low blood pressure), asthma, diabetes, or an overactive thyroid gland. It is generally not recommended during pregnancy or breastfeeding without consulting a doctor. Avoid alcohol consumption as it may further lower blood pressure and increase dizziness. This medicine may cause dizziness or weakness, so caution is advised when driving or operating heavy machinery.

• Storage: Store NEBISTAR 10 MG TABLET at room temperature, below 30°C, away from direct sunlight and moisture, and out of the reach of children.

NEBISTAR 10 MG TABLET, containing Nebivolol, is a beta-blocker primarily used to manage high blood pressure (hypertension). It can also be prescribed to prevent future heart attacks and strokes, and in some cases, to manage symptoms of an overactive thyroid gland or mild to moderate chronic heart failure in elderly patients.

Here are some frequently asked questions about NEBISTAR 10 MG TABLET:

What is NEBISTAR 10 MG TABLET used for?

NEBISTAR 10 MG TABLET is primarily used to treat high blood pressure (hypertension). It also helps in the prevention of heart attacks and strokes. In some instances, it may be used to manage mild and moderate chronic heart failure in patients over 70 years of age, and to relieve symptoms caused by an overactive thyroid gland.

How does NEBISTAR 10 MG TABLET work?

NEBISTAR 10 MG TABLET contains Nebivolol, which belongs to a class of medicines called beta-blockers. It works by selectively blocking beta-1 adrenergic receptors in the heart and blood vessels. This action slows down the heart rate and reduces the force of heart contractions, thereby decreasing the heart's workload and lowering blood pressure. Additionally, Nebivolol has a unique ability to stimulate the production of nitric oxide, a natural substance that helps relax and widen blood vessels, further contributing to reduced peripheral vascular resistance and improved blood flow.

What is the usual dosage of NEBISTAR 10 MG TABLET?

For most patients with high blood pressure, the recommended starting dose is typically 5 mg once daily, which can be taken with or without food. The dose may be increased at 2-week intervals up to a maximum of 40 mg per day, as needed, under medical supervision. For mild to moderate chronic heart failure in elderly patients (above 70 years), the initial dose is often 1.25 mg once daily, gradually increased over 1-2 weeks to a maximum of 10 mg once daily, adjusted based on the patient's response and tolerability. Dosage adjustments may also be necessary for individuals with severe kidney or moderate liver impairment. It's crucial to follow your doctor's instructions exactly and not to stop the medication abruptly.

What are the possible side effects of NEBISTAR 10 MG TABLET?

Common side effects of NEBISTAR 10 MG TABLET may include headache, dizziness, fatigue, nausea, diarrhea, constipation, and swelling in the feet or hands (edema). Less common but potentially serious side effects can include severe bradycardia (very slow heart rate), significant drops in blood pressure, shortness of breath, and bronchospasm. If you experience any persistent or severe side effects, or notice new ones, you should consult your doctor.

Is NEBISTAR 10 MG TABLET safe during pregnancy or breastfeeding?

NEBISTAR (Nebivolol) is generally not recommended during pregnancy unless the potential benefit justifies the potential risk to the fetus. It is considered a Category C medication during pregnancy. For breastfeeding mothers, it is not known if nebivolol passes into breast milk, but beta-blockers can cause serious adverse effects such as bradycardia in nursing infants. Therefore, Nebistar 10 MG TABLET is not recommended for use while breastfeeding. Labetalol, metoprolol, or propranolol are generally preferred beta-blockers if clinically appropriate during breastfeeding.

Can NEBISTAR 10 MG TABLET be taken with other medications?

NEBISTAR 10 MG TABLET can interact with various medications. Co-administration with other beta-blockers or non-dihydropyridine calcium channel blockers (like verapamil or diltiazem) can lead to excessive reductions in heart rate, blood pressure, and cardiac contractility. Medications that inhibit the CYP2D6 enzyme (e.g., quinidine, fluoxetine, paroxetine) can increase nebivolol levels in the blood, potentially enhancing its effects and side effects. If you are taking digitalis glycosides, there's an increased risk of bradycardia. Nebivolol can also mask symptoms of low blood sugar, so diabetic patients taking antidiabetic medicines like metformin or insulin should monitor their blood glucose levels closely. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken?

Several precautions should be observed when taking NEBISTAR 10 MG TABLET:

• Abrupt Withdrawal: Do not stop taking this medicine suddenly, especially if you have heart problems, as it can lead to a sudden rise in blood pressure, worsening chest pain (angina), irregular heart rate, or even a heart attack. Your doctor will gradually reduce the dosage over 1-2 weeks if discontinuation is necessary.
• Medical Conditions: Use with caution if you have bronchospastic diseases (like asthma), diabetes, liver or kidney problems, peripheral vascular disease, or an overactive thyroid gland, as Nebistar may worsen these conditions or mask their symptoms.
• Driving and Operating Machinery: Nebistar may cause dizziness, fatigue, or weakness, especially when you first start treatment or after a dose change. Avoid driving or operating heavy machinery until you know how the medication affects you.
• Alcohol Consumption: Avoid alcohol consumption while taking Nebistar 10 MG TABLET, as it may increase dizziness and further lower blood pressure.
• Surgery: Inform your doctor or dentist if you are taking Nebistar before any surgery, as it may increase the risk of very low blood pressure.

What happens if a dose is missed?

If you miss a dose of NEBISTAR 10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can lead to dangerous side effects.

How should NEBISTAR 10 MG TABLET be stored?

NEBISTAR 10 MG TABLET should be stored in a closed container at room temperature, typically between 10ºC to 30ºC (50ºF to 86ºF). Keep it in a cool and dry place, away from moisture, heat, and direct light. Ensure it is kept out of the reach of children and pets. Do not keep outdated medicine or medicine no longer needed.