Infura Tab

INFURA TAB

INFURA TAB is a prescription antibiotic medication manufactured by RPG Life Sciences Limited, primarily used for treating and preventing bacterial infections of the urinary tract.

• Name:

  • Brand Name: INFURA TAB
  • Common Name: Nitrofurantoin

• Composition:

  • Each film-coated sustained-release tablet contains Nitrofurantoin IP 100mg.

• Uses: INFURA TAB is prescribed for the management and prevention of various bacterial infections affecting the urinary system.

  • Urinary Tract Infections (UTIs): This includes bladder infections (cystitis) and kidney infections caused by susceptible bacteria.
  • Recurrent UTIs: It can also be used as a preventive measure against recurring urinary tract infections. INFURA TAB works by killing bacteria present in the urethra, bladder, and/or kidneys by disrupting their genetic material, thereby stopping their growth. It is effective against susceptible strains of bacteria such as Escherichia coli, Enterococcus, Staphylococcus, Citrobacter, Klebsiella, and Enterobacter species. It is important to note that it is not effective against viral infections like the common cold or flu.

• Dosage and Administration:

  • INFURA TAB should be taken in the dose and duration as advised by a doctor.
  • The tablet should be swallowed whole with a glass of water or milk and should not be chewed, crushed, or broken.
  • It is recommended to take INFURA TAB with food or milk to enhance absorption and minimize gastrointestinal side effects like stomach upset.
  • It is crucial to complete the full prescribed course of treatment, even if symptoms improve earlier, to ensure the complete eradication of the infection and prevent antibiotic resistance.
  • Typical adult dosage for urinary tract infections is often 100 mg, taken 2 to 4 times daily for 7 days, but this can vary based on the severity of the condition and patient response.

• Side Effects:

  • Common Side Effects: Nausea, vomiting, loss of appetite (anorexia), diarrhea, headache, drowsiness, dizziness, gas, stomach upset, and skin rash. It may also cause urine to turn a dark yellow or brown color, which is considered normal.
  • Serious Side Effects (Rare): Sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips, widespread rash or itching, fever, chills, cough, shortness of breath (lung reaction), yellowing of the skin or whites of the eyes (jaundice/liver inflammation), nerve damage (characterized by pain and numbness in hands and feet), and hemolytic anemia (abnormal destruction of red blood cells leading to weakness and fatigue). If any serious side effects occur, discontinue the medicine and consult a doctor immediately.

• Precautions:

  • Allergies: Do not take INFURA TAB if you are allergic to Nitrofurantoin or any of its ingredients.
  • Kidney/Liver Conditions: Not recommended for patients with severe kidney impairment (eGFR less than 45 ml/minute), a history of jaundice, or liver problems caused by previous Nitrofurantoin use. Use with caution in patients with lung or liver disease.
  • Pregnancy and Breastfeeding: Not recommended during the last two to four weeks of pregnancy, or during labor and delivery, due to potential harm to the baby. Use with caution in breastfeeding women, as it may pass into breast milk.
  • Other Medical Conditions: Caution is advised for patients with anemia, diabetes (it may interfere with urine tests for sugar), any illness causing severe weakness, electrolyte imbalance, vitamin B deficiency, porphyria (a blood disorder), or glucose-6-phosphate dehydrogenase (G6PD) deficiency due to the risk of hemolytic anemia.
  • Driving and Operating Machinery: This medicine may cause dizziness and drowsiness; therefore, avoid driving or operating heavy machinery.
  • Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking. Interactions can occur with antacids (like magnesium trisilicate), medicines for gout (e.g., probenecid, sulfinpyrazone), medicines that slow gastric passage (e.g., atropine, hyoscine), carbonic anhydrase inhibitors (e.g., acetazolamide), and medicines that make urine less acidic (e.g., potassium citrate mixture).
  • Alcohol and Grapefruit: Avoid consuming alcohol while taking INFURA TAB as it may increase the risk of side effects. Grapefruit should also be avoided.
  • Elderly and Infants: Use with caution in elderly patients. It is avoided for use in infants below 3 months of age.

• Storage:

  • Store INFURA TAB in a cool and dry place, ideally at room temperature between 10°C to 25°C or below 30°C.
  • Protect it from sunlight and moisture.
  • Keep out of sight and reach of children.

INFURA TAB by RPG LIFE SCIENCES LIMITED contains Nitrofurantoin, an antibiotic primarily used to treat and prevent bacterial infections of the urinary tract.

What is INFURA TAB used for?

INFURA TAB is prescribed for the treatment and prevention of bacterial infections of the urinary tract (UTIs), including bladder infections (cystitis) and kidney infections. It is effective against susceptible strains of bacteria that cause these infections.

How does INFURA TAB work?

INFURA TAB contains Nitrofurantoin, which is an antibiotic. It works by entering bacterial cells and destroying their genetic material, thereby inhibiting their growth and killing the bacteria responsible for the infection. It also prevents the formation of the bacterial cell wall and interferes with DNA and RNA synthesis.

What is the usual dosage for INFURA TAB?

The dosage of INFURA TAB should be strictly followed as advised by your doctor. It is typically taken with food, milk, or juice to help with absorption and minimize stomach upset. It's crucial to complete the entire prescribed course of treatment, even if symptoms improve, to prevent the infection from returning and to avoid antibiotic resistance.

What are the possible side effects of INFURA TAB?

Common side effects may include nausea, vomiting, diarrhea, loss of appetite, and headaches. More serious but rare side effects can involve lung inflammation, liver damage (indicated by persistent itching, yellowing of skin or eyes, dark urine), and nerve damage (peripheral neuropathy, characterized by pain and numbness in hands and feet). If you experience severe or persistent side effects, contact your doctor immediately.

Is INFURA TAB safe during pregnancy or breastfeeding?

INFURA TAB is generally not recommended during pregnancy, especially in the last 2 to 4 weeks, during labor, or delivery, due to potential risks to the baby. If you are pregnant or planning to become pregnant, consult your doctor. For breastfeeding mothers, INFURA TAB should be used with caution as it may pass into breast milk and could be harmful to the infant, particularly those with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult your doctor before breastfeeding.

Can INFURA TAB be taken with other medications?

Certain medications can interact with INFURA TAB. These include antacids (especially those containing magnesium salts), medicines for gout like probenecid and sulfinpyrazone, medicines that slow food passage through the stomach (e.g., atropine, hyoscine), and carbonic anhydrase inhibitors (e.g., acetazolamide). It is important to inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions. Alcohol consumption should be avoided while taking INFURA TAB as it may cause adverse reactions like flushing and increased heart rate.

What precautions should be taken while taking INFURA TAB?

Do not take INFURA TAB if you are allergic to nitrofurantoin or have severe kidney problems (e.g., eGFR less than 45 mL/minute). Use with caution if you have lung or liver disease, anaemia, diabetes, G6PD deficiency, or electrolyte imbalances. INFURA TAB may cause dizziness or drowsiness, so it's advisable to avoid driving or operating heavy machinery until you know how the medicine affects you. It may also cause your urine to turn dark yellow or brown, which is a normal and harmless effect.

What happens if a dose of INFURA TAB is missed?

If you miss a dose of INFURA TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should INFURA TAB be stored?

INFURA TAB should be stored in a cool, dry place, typically at room temperature between 15°C and 30°C. Protect it from direct sunlight and moisture. Keep this medicine out of the sight and reach of children.