Gluvilda 50 Mg Tablet (15 Tab)

GLUVILDA 50 MG TABLET

GLUVILDA 50 MG TABLET, manufactured by Alkem Laboratories Ltd., is an oral antidiabetic medication used for the management of type 2 diabetes mellitus.

Composition

GLUVILDA 50 MG TABLET contains Vildagliptin 50mg as its active ingredient. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which works by increasing the levels of incretin hormones. These hormones stimulate the pancreas to release more insulin after meals and decrease glucagon production by the liver, thereby lowering elevated blood sugar levels.

Uses

GLUVILDA 50 MG TABLET is prescribed for adults with type 2 diabetes mellitus, particularly when blood sugar levels are not adequately controlled by diet and exercise alone. It can be used as a standalone treatment or in combination with other antidiabetic medicines. The medication helps improve insulin sensitivity, reduce glucose production by the liver, and prevent serious diabetes-related complications such as kidney damage, eyesight loss, nerve damage, diabetic foot ulcers, and cardiovascular risks.

Dosage and Administration

The typical dosage is one tablet (50mg) once daily. If prescribed twice daily, the first dose is usually taken in the morning and the second in the evening. It can be taken with or without food, but it's recommended to take it at the same time each day to maintain consistency. Tablets should be swallowed whole with water and not chewed, crushed, or broken. Dosage may be adjusted by a doctor based on the patient's condition and blood sugar levels.

Side Effects

Common Side Effects:

• Hypoglycemia (low blood sugar), especially when used with other diabetes medications
• Tremors
• Headache
• Dizziness
• Fatigue
• Nausea
• Nasopharyngitis (common cold symptoms)
• Constipation
• Joint pain
• Upper respiratory infections

Serious Side Effects (seek immediate medical attention):

• Signs of liver disease (e.g., loss of appetite, dark-colored urine, yellow skin and eyes, nausea)
• Signs of inflammation of the pancreas (e.g., severe and persistent abdominal pain, nausea, vomiting)
• Severe allergic reactions (e.g., anaphylaxis, angioedema, exfoliative skin conditions including Stevens-Johnson syndrome)

Precautions

• Type 1 Diabetes and Diabetic Ketoacidosis: GLUVILDA 50 MG TABLET is not for use in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
• Medical Conditions: Inform your doctor if you have a history of kidney disease (especially severe), liver disease (use with caution, avoid if severe), heart disease (including heart failure), or pancreatic issues (e.g., pancreatitis).
• Pregnancy and Breastfeeding: It is not recommended for use in pregnant or breastfeeding women. Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Pediatric Use: Not recommended for use in children and adolescents below 18 years of age.
• Elderly Patients: Use with caution in elderly patients (aged 65 years and above).
• Alcohol Consumption: Limit or avoid alcohol consumption as it may increase the risk of hypoglycemia (low blood sugar).
• Driving and Machinery: GLUVILDA 50 MG TABLET may cause dizziness. Exercise caution when driving or operating machinery until you know how the medicine affects you.
• Drug Interactions: Closely monitor if taking digoxin (a heart medicine) with GLUVILDA 50 MG TABLET. Inform your doctor about all other medications you are taking to prevent potential interactions.
• Treatment Adherence: Do not stop taking the medicine abruptly without consulting your doctor, as this can increase blood sugar levels and the risk of complications.
• Lifestyle: Adherence to a proper diet and regular exercise program is crucial for effective diabetes management alongside this medication.

Storage

Store GLUVILDA 50 MG TABLET in a cool and dry place, away from direct sunlight and moisture, preferably below 30°C. Keep out of sight and reach of children.

1. What is Gluvilda 50 MG Tablet used for?

Gluvilda 50 MG Tablet is an oral anti-diabetic medication primarily used to manage type 2 diabetes mellitus in adults. It is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels, and it can be used alone or in combination with other diabetes medications. By helping to control high blood sugar, it aids in preventing serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, and an increased risk of heart attack or stroke.

2. How does Gluvilda 50 MG Tablet work?

Gluvilda 50 MG Tablet contains Vildagliptin, which belongs to a class of medicines called DPP-4 inhibitors. It works by preventing the breakdown of certain chemical messengers known as incretin hormones (like GLP-1 and GIP) in the body. These hormones are released after meals and stimulate the pancreas to produce more insulin when blood sugar levels are high. Vildagliptin also helps to decrease the production of glucagon by the liver, which further helps to lower blood sugar levels. This dual action helps to regulate both fasting and post-meal blood sugar levels.

3. What is the usual dosage of Gluvilda 50 MG Tablet?

The dosage of Gluvilda 50 MG Tablet can vary depending on factors such as age, weight, medical condition, and other medications being taken. The recommended dose for most adult patients with type 2 diabetes is typically 50mg once or twice daily. It can be taken with or without food. It is crucial to follow your doctor's instructions regarding the dose and timing and not to alter it without consulting your doctor.

4. What are the possible side effects of Gluvilda 50 MG Tablet?

Common side effects of Gluvilda 50 MG Tablet can include low blood sugar levels (hypoglycemia), headache, dizziness, fatigue, nausea, tremors, and nasopharyngitis (common cold symptoms). Some patients may also experience constipation, joint pain, or swelling in the hands, ankles, or feet. More severe but less common side effects can include signs of liver disease (such as yellow skin/eyes or dark urine), or inflammation of the pancreas (severe abdominal pain, nausea, vomiting). If you experience severe or persistent side effects, you should consult your doctor.

5. Is Gluvilda 50 MG Tablet safe during pregnancy or breastfeeding?

Gluvilda 50 MG Tablet is generally not recommended during pregnancy. While limited human studies are available, animal studies have shown harmful effects on the developing baby. For breastfeeding mothers, the excretion of Gluvilda 50 MG Tablet in breast milk is unknown, and it is generally not recommended. It is important to consult your doctor to weigh the benefits and potential risks before using this medication if you are pregnant or breastfeeding.

6. Can Gluvilda 50 MG Tablet be taken with other medications?

Gluvilda 50 MG Tablet can be taken with other anti-diabetic medications, but concomitant use may increase the risk of low blood sugar (hypoglycemia). It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking, as some medications like water pills (diuretics), corticosteroids, thyroxine, digoxin (a heart medicine), warfarin, and certain cardiac drugs may interact with Gluvilda 50 MG Tablet. Your doctor may need to adjust dosages or monitor you closely for interactions.

7. What precautions should be taken while taking Gluvilda 50 MG Tablet?

Before taking Gluvilda 50 MG Tablet, inform your doctor if you have a history of kidney disease (especially moderate to severe impairment), liver disease, heart problems (like irregular heartbeat or heart failure), or pancreas problems (such as pancreatitis). Gluvilda 50 MG Tablet is not for use in type 1 diabetes or diabetic ketoacidosis. Regular monitoring of kidney and liver function may be advised. Be cautious while driving or operating machinery if you experience dizziness. Alcohol consumption should be avoided as it can affect blood sugar levels.

8. What happens if a dose of Gluvilda 50 MG Tablet is missed?

If you miss a dose of Gluvilda 50 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

9. How should Gluvilda 50 MG Tablet be stored?

Gluvilda 50 MG Tablet should be stored in a cool and dry place, away from direct sunlight, heat, and moisture. It should be kept out of sight and reach of children, typically at temperatures below 25°C or 30°C.