Revlamer 400 Mg Tablet (10 Tab)

REVLAMER 400 MG TABLET

Name: REVLAMER 400 MG TABLET. The common name for its active ingredient is Sevelamer.

Composition: Each tablet contains Sevelamer 400 mg.

Uses: REVLAMER 400 MG TABLET is prescribed to control elevated phosphate levels in the blood, a condition known as hyperphosphatemia. It is primarily used in adult patients with chronic kidney disease (CKD), particularly those undergoing dialysis (hemodialysis or peritoneal dialysis). The medicine works by binding to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream and thereby lowering serum phosphate concentrations. This helps to prevent complications such as bone disorders and cardiovascular diseases associated with high phosphate levels.

Dosage and Administration: REVLAMER 400 MG TABLET should be taken orally with meals, as directed by a healthcare professional. Tablets should be swallowed whole with water and not crushed, chewed, or broken. The specific dose and duration of treatment will depend on the patient's condition and response to medication. It is typically taken three times daily. Patients should avoid taking other medications 1 hour before or 3 hours after taking Revlamer to prevent potential absorption interference.

Side Effects: Common side effects may include nausea, vomiting, abdominal pain, constipation, diarrhea, indigestion, and flatulence. Patients may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in their blood; supplements may be prescribed by a doctor if necessary. Serious side effects, though rare, can include intestinal obstruction/blockage, rupture in the intestinal wall, severe inflammation of the large bowel, or an allergic reaction.

Precautions: REVLAMER 400 MG TABLET is not recommended for patients with low blood phosphate levels or those with bowel obstruction. Caution is advised for individuals with swallowing disorders, motility problems in the stomach or bowel, severe constipation, or those who have undergone major stomach or bowel surgery. Regular monitoring of serum phosphate levels, as well as vitamins D, A, E, K, and folic acid, is essential. The medicine may interact with other drugs such as certain antibiotics (e.g., ciprofloxacin), thyroid hormone medications (e.g., levothyroxine), immunosuppressants (e.g., mycophenolate), and vitamin D analogues, potentially reducing their effectiveness or absorption. Pregnant or breastfeeding women should consult their doctor before using this medication.

Storage: Store REVLAMER 400 MG TABLET in a cool, dry place, protected from sunlight, moisture, and extreme heat or cold. The storage temperature should not exceed 30°C. Keep the medicine out of sight and reach of children and pets.

REVLAMER 400 MG TABLET is a medication used to manage high phosphate levels in the blood, particularly in individuals with severe kidney disease who are undergoing dialysis. It contains Sevelamer, which is a phosphate-binding agent.

Here are some frequently asked questions about REVLAMER 400 MG TABLET:

What is REVLAMER 400 MG TABLET used for?

REVLAMER 400 MG TABLET is primarily used to control elevated phosphate levels in the blood, a condition known as hyperphosphatemia. This is common in patients with chronic kidney disease, especially those on dialysis (hemodialysis or peritoneal dialysis). By reducing phosphate levels, it helps prevent complications such as bone pain, itching, bone disorders, and complications related to the heart and blood vessels.

How does REVLAMER 400 MG TABLET work?

REVLAMER 400 MG TABLET contains sevelamer, a non-absorbed polymer that acts as a phosphate binder. When taken with food, it binds to phosphate in the gastrointestinal tract, forming an insoluble complex that cannot be absorbed into the bloodstream. This complex is then excreted through feces, effectively lowering the amount of phosphate in the blood. Unlike calcium-based binders, it does not increase calcium levels.

What is the usual dosage for REVLAMER 400 MG TABLET?

The dosage of REVLAMER 400 MG TABLET is determined by your doctor and depends on your individual phosphate levels and medical condition. It is typically taken with food, usually three times a day. You should always follow your doctor's instructions regarding the dose and duration of treatment. Do not crush, chew, or break the tablets; swallow them whole with a glass of water.

What are the possible side effects of REVLAMER 400 MG TABLET?

Common side effects may include nausea, vomiting, abdominal pain, constipation, diarrhea, indigestion, and flatulence (gas). Less common but serious side effects can include intestinal blockage or rupture, which may present as severe abdominal pain, bloating, or severe constipation. If any side effects persist or become severe, it's important to consult your doctor immediately.

Is REVLAMER 400 MG TABLET safe during pregnancy or breastfeeding?

During pregnancy, REVLAMER 400 MG TABLET should be used only if clearly necessary, as there is limited information on its safety in humans, though animal studies have shown harmful effects on the developing baby. For breastfeeding, it is generally considered probably safe as it is not absorbed systemically and is not expected to pass into breast milk. However, it's always best to consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can REVLAMER 400 MG TABLET be taken with other medications?

REVLAMER 400 MG TABLET can interact with several medications, potentially reducing their absorption and effectiveness. It's crucial to inform your doctor about all medicines, supplements, or herbal products you are taking. For instance, it may decrease the absorption of antibiotics like ciprofloxacin, immunosuppressants (e.g., ciclosporin, tacrolimus, mycophenolate mofetil), and thyroid hormone medications like levothyroxine. Your doctor may advise taking these medications at least 1 hour before or 3 hours after taking REVLAMER to minimize interactions.

What precautions should be taken while using REVLAMER 400 MG TABLET?

Inform your doctor if you have swallowing disorders, severe constipation, a history of major stomach or bowel surgery, or inflammatory bowel disease, as REVLAMER may worsen these conditions. Regular monitoring of serum phosphate levels, as well as levels of vitamins A, D, E, K, and folic acid, is recommended, as REVLAMER can decrease their absorption. Following a diet low in phosphorus, as advised by your doctor, is also important.

What happens if a dose is missed?

If you miss a dose of REVLAMER 400 MG TABLET, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should REVLAMER 400 MG TABLET be stored?

Store REVLAMER 400 MG TABLET at room temperature, below 30°C, away from moisture, heat, and direct light. Keep it out of reach and sight of children and pets.