Brivgard 75mg Tab

BRIVGARD 75MG TABLET

BRIVGARD 75MG Tablet is a medication manufactured by LUPIN LTD.

• Name:

  • Common Name: Brivaracetam
  • Brand Name: BRIVGARD 75MG. Other brand names for Brivaracetam include Briviact.

• Composition:

  • Each film-coated tablet contains Brivaracetam 75 mg.

• Uses: BRIVGARD 75MG is an anti-epileptic drug primarily used as an adjunctive therapy for the treatment of partial-onset seizures (also known as focal seizures) with or without secondary generalization in patients with epilepsy. It is approved for use in adults, adolescents, and children from 1 month of age. Brivaracetam works by selectively binding to synaptic vesicle protein 2A (SV2A) in the brain, which helps to stabilize abnormal neuronal activity and reduce the occurrence of seizures.

• Dosage and Administration:

  • BRIVGARD 75MG tablets are for oral administration and should be swallowed whole with liquid, with or without food. Do not crush, chew, or break the tablets.
  • Adults (16 years and older): The usual starting dose is 50 mg twice daily (100 mg per day), which may be adjusted based on individual response and tolerability, typically ranging from 50 mg/day to 200 mg/day (25 mg to 100 mg twice daily).
  • Pediatric Patients (1 month to less than 16 years): Dosage is weight-based and must be determined by a healthcare provider.
  • Hepatic Impairment: A lower starting dose and maximum daily dose are recommended for patients with liver problems.
  • Discontinuation: Abrupt withdrawal should be avoided to minimize the risk of increased seizure frequency or status epilepticus; gradual reduction is generally recommended under medical supervision.

• Side Effects:

  • Common Side Effects: Drowsiness, dizziness, fatigue, nausea, vomiting, and constipation.
  • Serious Side Effects: Include changes in mood or behavior such as depression, anxiety, agitation, aggression, irritability, and psychotic symptoms (e.g., hallucinations, delusions). Suicidal thoughts or actions have also been reported. Patients may also experience problems with coordination and balance. Serious allergic reactions like bronchospasm, angioedema (swelling of the face, eyelids, lips, tongue, throat), and difficulty breathing or swallowing can occur.

• Precautions:

  • Close monitoring by a doctor is crucial, especially during the initial months of treatment, to assess for effectiveness and adverse reactions.
  • Patients should be monitored for any unusual changes in mood or behavior, depression, or suicidal thoughts.
  • Due to potential drowsiness, dizziness, or coordination problems, patients should avoid driving or operating heavy machinery until they understand how the medicine affects them.
  • Inform your doctor if you have liver problems, as dose adjustments may be necessary.
  • Alcohol consumption should be avoided as it can increase the risk of side effects like drowsiness and dizziness.
  • Use with caution during pregnancy and breastfeeding; consult a healthcare provider.
  • Inform your doctor about all other medications you are taking, as BRIVGARD can interact with certain drugs (e.g., carbamazepine, rifampin).

• Storage:

  • Store BRIVGARD 75MG tablets in a closed container at room temperature, between 15°C to 30°C (59°F to 86°F), away from heat, moisture, and direct light.
  • Do not freeze the oral solution (if applicable for other forms of Brivaracetam).
  • Keep out of the reach of children.

What is BRIVGARD 75MG Tablet used for?

BRIVGARD 75MG Tablet is an anti-epileptic medicine primarily used to treat partial-onset seizures in individuals with epilepsy. It can be prescribed for adults, adolescents, and children aged one month and older, either alone (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) to help control seizures.

How does BRIVGARD 75MG Tablet work?

BRIVGARD 75MG Tablet contains Brivaracetam, which works by selectively binding to synaptic vesicle protein 2A (SV2A) in the brain. This action helps regulate abnormal neuronal electrical activity and controls the excessive spread of electrical impulses that lead to epileptic seizures.

What is the usual dosage for BRIVGARD 75MG Tablet?

The dosage of BRIVGARD 75MG Tablet is determined by your doctor based on individual factors such as age, the severity of your condition, and your response to treatment. It should be swallowed whole with a glass of water, with or without food, preferably at the same time each day for optimal results. Do not crush, chew, or break the tablet.

What are the possible side effects of BRIVGARD 75MG Tablet?

Common side effects may include drowsiness, dizziness, fatigue, nausea, vomiting, irritability, anxiety, mood changes, headache, and flu-like symptoms. More serious but less common side effects can involve behavioral changes, aggression, agitation, and in some individuals, thoughts of self-harm. If you experience severe or persistent side effects, or any concerning mood or behavioral changes, contact your doctor immediately.

Is BRIVGARD 75MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: BRIVGARD 75MG Tablet is generally not recommended during pregnancy unless your doctor considers it absolutely necessary, as there is limited data in humans and animal studies have indicated potential harm to the developing baby.

Breastfeeding: It is generally not recommended during breastfeeding because Brivaracetam may pass into breast milk, and its effects on the nursing infant are not fully known. If usage is advised by your doctor while breastfeeding, the infant should be closely monitored for drowsiness, agitation, and adequate weight gain.

Can BRIVGARD 75MG Tablet be taken with other medications?

BRIVGARD 75MG Tablet can interact with other medications. For instance, certain anti-epileptic medicines like carbamazepine and phenytoin, and antibiotics like rifampin, may decrease the levels of Brivaracetam in your body. Taking it with Central Nervous System (CNS) depressants such as opioids or antidepressants can increase drowsiness and sedation. Herbal remedies like St. John's wort can also interact. Always inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while on BRIVGARD 75MG Tablet?

• Alcohol: Avoid consuming alcohol as it can increase drowsiness, dizziness, and other side effects.
• Driving & Machinery: This medicine may cause drowsiness, dizziness, or affect your vision. Avoid driving or operating heavy machinery until you understand how it affects you.
• Liver/Kidney Conditions: Inform your doctor if you have liver or kidney problems, as your dosage may need adjustment.
• Discontinuation: Do not stop taking BRIVGARD 75MG Tablet suddenly, even if you feel better, as abrupt discontinuation can worsen seizures. Any changes to your treatment should be discussed with your doctor for a gradual discontinuation plan.
• Mood Changes: Monitor for any unusual changes in mood or behavior, including thoughts of self-harm, and report them to your doctor immediately.

What happens if a dose of BRIVGARD 75MG Tablet is missed?

If you miss a dose of BRIVGARD 75MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects.

How should BRIVGARD 75MG Tablet be stored?

Store BRIVGARD 75MG Tablet in a cool and dry place, away from direct sunlight and moisture. Keep it in its original packaging and out of the reach of children and pets. It should generally be stored below 25°C or 30°C.