Olymprix M 1000 (15 Tab)

OLYMPRIX M 1000 (15 TAB) by ALKEM LABORATORIES LTD is a medication prescribed for the management of Type 2 diabetes mellitus.

Name

• Brand Name: Olymprix M 1000

Composition

• Active Ingredients: Metformin (1000mg) and Teneligliptin (20mg).
  • Metformin, a biguanide, reduces glucose production in the liver, decreases intestinal glucose absorption, and enhances insulin sensitivity.
  • Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, increases insulin secretion and lowers glucagon levels, particularly after meals.

Uses

• Primarily used to control high blood sugar levels in adults with Type 2 diabetes mellitus.
• It is prescribed when diet and exercise alone, or other anti-diabetic medications, do not adequately control blood sugar levels.
• Helps improve glycemic control, insulin sensitivity, and reduces the risk of long-term diabetes complications such as kidney damage, eye damage, and nerve problems.

Dosage and Administration

• Take as instructed by your doctor, usually once daily.
• Can be taken with or after a meal to minimize stomach upset.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• Maintain a consistent dosing schedule.

Side Effects

• Common Side Effects: Nausea, vomiting, diarrhea, upset stomach, headache, abdominal discomfort, flatulence, and low blood sugar levels (hypoglycemia).
• Serious Side Effects: Lactic acidosis (a rare but serious condition indicated by symptoms like abdominal pain, muscle cramps, vomiting, extreme fatigue, and breathing difficulties), and Vitamin B12 deficiency with long-term use.

Precautions

• Contraindications: Allergic to its components, severe kidney or liver problems, Type 1 diabetes, diabetic ketoacidosis, severe heart problems (e.g., congestive heart failure), severe infection, recent severe trauma or surgery, or history of pancreatitis.
• Warnings: Caution is advised in patients with heart diseases as it may elevate the risk of heart failure. Inform your doctor if you have kidney, liver, or heart issues, pancreatic problems, or a history of alcohol abuse.
• Pregnancy and Breastfeeding: Generally, insulin is preferred in pregnancy-related diabetes. Not recommended during breastfeeding as it may pass into breast milk.
• Alcohol: Avoid excessive alcohol consumption due to increased risk of lactic acidosis.
• Drug Interactions: Cationic medicines (e.g., digoxin, ranitidine, amiloride) and carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide) may interact.
• Regular monitoring of blood sugar levels, kidney function, and vitamin B12 levels is recommended.

Storage

• Store in a cool and dry place, away from direct sunlight, moisture, and heat.
• Keep out of reach of children.
• Store below 30°C.

What is Olymprix M 1000 used for?

Olymprix M 1000 is primarily used to control high blood sugar levels in adults with Type 2 diabetes mellitus. It helps manage the condition when diet and exercise alone are not sufficient. By regulating blood sugar, it aims to reduce the risk of serious complications such as kidney damage, eye damage, nerve problems, heart disease, and stroke.

How does Olymprix M 1000 work?

Olymprix M 1000 is a combination medication containing two active ingredients: Metformin and Teneligliptin. Metformin, a biguanide, works by reducing the amount of glucose produced by the liver, decreasing glucose absorption from the intestines, and improving the body's sensitivity to insulin. Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, increases the levels of natural substances in the body that stimulate the pancreas to release more insulin and reduce glucagon levels, thereby lowering blood sugar.

What is the usual dosage for Olymprix M 1000?

The dosage of Olymprix M 1000 should be strictly as prescribed by your doctor, as it depends on your specific condition and blood sugar levels. It is generally recommended to take the tablet once daily, or sometimes twice daily, with or after meals to minimize stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken.

What are the possible side effects of Olymprix M 1000?

Common side effects include diarrhea, nausea, vomiting, upset stomach, headache, and abdominal discomfort. Low blood sugar (hypoglycemia) is also a possible side effect, particularly if taken with other diabetes medications like insulin or sulfonylureas. Less common but serious side effects can include lactic acidosis (a build-up of lactic acid in the blood) and, with long-term use, a deficiency in Vitamin B12. If side effects persist or worsen, consult your doctor.

Is Olymprix M 1000 safe during pregnancy or breastfeeding?

Olymprix M 1000 should generally be avoided during pregnancy unless specifically recommended by a doctor, as safe use has not been established. It is considered unsafe or contraindicated during breastfeeding because the drug components may pass into breast milk and potentially harm the nursing infant. It is crucial for pregnant or breastfeeding women to consult their healthcare provider before taking this medication.

Can Olymprix M 1000 be taken with other medications?

Yes, but it's important to inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, to prevent potential interactions. Olymprix M 1000 can interact with other antidiabetic agents (increasing the risk of hypoglycemia), cationic medicines (like digoxin, ranitidine, amiloride), and carbonic anhydrase inhibitors (like topiramate, acetazolamide), which can increase the risk of lactic acidosis. Steroids, thyroxine, and certain blood pressure medications can also affect its efficacy or increase side effects.

What precautions should be taken while taking Olymprix M 1000?

Before starting Olymprix M 1000, inform your doctor if you have a history of kidney, liver, or heart disease (including congestive heart failure), pancreatic issues, or if you consume a significant amount of alcohol. Avoid excessive alcohol intake during treatment as it increases the risk of lactic acidosis. Your doctor will likely monitor your kidney function and blood sugar levels regularly throughout your treatment. Be aware of the symptoms of low blood sugar (hypoglycemia) and how to manage them. This medicine is not suitable for Type 1 diabetes or diabetic ketoacidosis. Long-term use may require monitoring of Vitamin B12 levels.

What happens if a dose of Olymprix M 1000 is missed?

If you miss a dose of Olymprix M 1000, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Olymprix M 1000 be stored?

Olymprix M 1000 should be stored in a cool, dry place, away from direct sunlight and moisture. The ideal storage temperature is typically below 30°C or between 10°C to 25°C. Always keep this medicine out of the sight and reach of children and pets. Do not keep outdated medicine; ask your pharmacist how to dispose of unused medication.