Isonorm 60 Sr

ISONORM 60 SR

Name

• Brand Name: ISONORM 60 SR
• Common Name: Isosorbide Mononitrate Extended Release Tablet

Composition

• Active Ingredients: Each tablet contains Isosorbide Mononitrate 60 mg (sustained-release or prolonged-release form).

Uses

ISONORM 60 SR is a nitrate vasodilator primarily used for the prevention and long-term management of heart-related chest pain (angina pectoris). It works by relaxing and widening blood vessels, particularly those of the heart, which improves blood flow and oxygen delivery to the heart muscle, thereby reducing its workload. It is important to note that ISONORM 60 SR is used to prevent angina attacks and will not treat an angina attack that has already begun.

It is also used in the management of:

• Chronic stable angina
• Heart failure (to ease the workload on the heart)
• Coronary artery disease
• Hypertensive emergency (to help lower blood pressure quickly)

Dosage and Administration

ISONORM 60 SR tablets are typically taken orally once daily, usually in the morning. It can be taken with or without food. The tablet should be swallowed whole and not crushed, chewed, or broken. The dosage and frequency are determined by the doctor based on the patient's condition and response to treatment. Consistent adherence to the prescribed dosing schedule is crucial to maintain effectiveness and prevent tolerance development. Do not stop taking the medicine abruptly, as this can increase the risk of chest pain.

Side Effects

Common Side Effects:

• Headache (often resolves after a few days of treatment)
• Dizziness
• Flushing (warmth and redness in the face, neck, or chest)
• Nausea
• Weakness/Fatigue
• Abdominal pain
• Diarrhea
• Changes to heart rate (can be a decrease or increase)

Serious Side Effects (less common):

• Bluish discoloration of lips, fingernails, palms, or hands
• Irregular heartbeat
• Low blood pressure (hypotension), which can lead to fainting
• Difficulty breathing or swallowing

Precautions

• Allergies: Do not use if allergic to Isosorbide Mononitrate or any other nitrate.
• Low Blood Pressure: Use with caution in patients with low blood pressure as it can further decrease blood pressure.
• Heart Conditions: Caution is advised in patients with recent heart attack, heart failure, or obstructive heart disease.
• Glaucoma: Use with caution in patients with glaucoma.
• Liver/Kidney Impairment: Caution is advised in patients with liver or kidney problems.
• Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding.
• Alcohol Interaction: Avoid alcohol consumption as it can increase the risk of dizziness, low blood pressure, and other severe side effects.
• Drug Interactions:
  • Do not take with medications for erectile dysfunction (e.g., sildenafil or tadalafil) as it can cause a severe drop in blood pressure.
  • Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, to avoid interactions.
• Driving and Operating Machinery: May cause dizziness, blurred vision, or sleepiness; avoid activities requiring high mental alertness until you know how the medicine affects you.

Storage

Store ISONORM 60 SR tablets below 30°C in their original container. Keep the medicine out of the reach of children and pets, and protect it from light and moisture.

Here are frequently asked questions about ISONORM 60 SR:

What is ISONORM 60 SR used for?

ISONORM 60 SR is primarily used to prevent and treat angina pectoris, a type of chest pain caused by reduced blood flow to the heart muscle. It also helps in the long-term management of coronary heart disease, can be used in cases of hypertensive emergency, and assists in managing heart failure.

How does ISONORM 60 SR work?

ISONORM 60 SR contains Isosorbide Mononitrate, which belongs to a class of medicines called nitrate vasodilators. It works by relaxing and widening the blood vessels, particularly those supplying the heart. This action improves blood flow and oxygen supply to the heart muscle, and reduces the heart's workload by decreasing the amount of blood returning to it.

What is the usual dosage for ISONORM 60 SR?

The dosage of ISONORM 60 SR is determined by your doctor and may vary based on your condition and its severity. It is typically taken orally once daily, often in the morning. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. It can be taken with or without food. Always follow your doctor's prescribed dosage and schedule.

What are the possible side effects of ISONORM 60 SR?

Common side effects may include headache, dizziness, nausea, flushing (warmth and redness in the face, neck, or chest), faster heartbeat (tachycardia), low blood pressure, weakness, and fatigue. If any side effects worsen or persist, consult your doctor.

Is ISONORM 60 SR safe during pregnancy or breastfeeding?

ISONORM 60 SR is generally not recommended during the first three months of pregnancy. If you are pregnant or planning to become pregnant, or are breastfeeding, it is crucial to consult your doctor before taking this medicine to discuss the potential risks and benefits.

Can ISONORM 60 SR be taken with other medications?

It is very important to inform your doctor about all other medications you are taking. ISONORM 60 SR should not be taken with medicines for erectile dysfunction (e.g., sildenafil, tadalafil, alprostadil, vardenafil, udenafil) as this can cause a dangerous drop in blood pressure. Caution is also advised when taken with other blood pressure medications (like calcium channel blockers, ACE inhibitors, ARBs, beta-blockers, diuretics) or tricyclic antidepressants, as it may lead to excessive blood pressure lowering.

What precautions should be taken while taking ISONORM 60 SR?

Avoid consuming alcohol while taking ISONORM 60 SR, as it can increase the risk of dizziness, low blood pressure, and other severe side effects. Do not drive or operate heavy machinery if you experience dizziness, blurred vision, or sleepiness. Inform your doctor about any history of liver or kidney problems, low blood pressure, glaucoma, or certain heart conditions. Do not stop taking the medicine suddenly without consulting your doctor, as abrupt discontinuation can worsen your condition. Avoid grapefruit or grapefruit juice.

What happens if a dose of ISONORM 60 SR is missed?

If you miss a dose of ISONORM 60 SR, take it as soon as you remember, provided it is within 12 hours of your scheduled dose. If more than 12 hours have passed or it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ISONORM 60 SR be stored?

ISONORM 60 SR should be stored below 30°C, preferably at room temperature (20-25°C). Keep the medicine in its original container, away from direct light, heat, and moisture, and out of the reach of children and pets.

Why might I develop tolerance to ISONORM 60 SR, and how can it be avoided?

Over time, your body may develop a tolerance to ISONORM 60 SR, meaning the same dose might become less effective. To help prevent this, it's crucial to follow your prescribed dosing schedule strictly and not alter it without consulting your doctor.