Baclof (strawberry Flavour) Liquid 100 Ml

BACLOF (STRAWBERRY FLAVOUR) LIQUID 100 ML by INTAS PHARMACEUTICALS LTD.

Name

• Common Name: Baclofen Oral Solution
• Brand Name: BACLOF (Strawberry Flavour) Liquid
• Manufacturer: Intas Pharmaceuticals Ltd.

Composition

• Active Ingredient: Baclofen 5 mg/5 ml
• Excipients: Includes methyl parahydroxybenzoate (E218), sorbitol liquid (non-crystallising) (E420), carmellose sodium (E466), propylene glycol (E1520) as part of the raspberry/strawberry flavour, and purified water.

Uses

BACLOF Liquid is a muscle relaxant used to alleviate muscle spasms, rigidity, tension, and stiffness. It is prescribed for conditions affecting the skeletal muscles and nervous system, such as:

• Multiple Sclerosis
• Spinal Cord Injuries and disorders
• Cerebral Palsy
• Motor Neuron Disease
• Stroke (cerebrovascular accidents)
• Other conditions causing spasticity affecting the brain, spinal cord, and nervous system It works by blocking chemical messengers in the brain and spinal cord to relieve muscle stiffness and improve movement.

Dosage and Administration

The dosage of BACLOF Liquid should be individualized based on the patient's response and requirements, using the lowest effective dose.

• Adults: Treatment typically starts with 5 mg (5 ml of the liquid) three times a day. The dose may be gradually increased by 5 mg every three days, as needed and tolerated. The usual daily dosage for maintenance therapy ranges between 0.75 and 2 mg/kg body weight. The maximum daily dose generally does not exceed 80 mg (80 ml), but up to 100-120 mg may be used under strict hospital supervision.
• Children: For children aged 12 years and older, the dosing schedule is similar to adults. For children younger than 12 years, the use and dose must be determined by a doctor, often based on weight or age.
• Administration: Take BACLOF Liquid orally, with or after food. Measure the dose accurately using a special measuring spoon, oral syringe, or medicine cup provided by the pharmacist. Do not use a household teaspoon. Do not stop taking this medicine suddenly; the dose should be gradually reduced over 1 to 2 weeks under medical supervision to avoid severe side effects.

Side Effects

Common side effects may include:

• Drowsiness
• Dizziness
• Weakness or tiredness
• Nausea and constipation
• Headache
• Increased or frequent urination
• Dry mouth Serious side effects, though less common, can include:
• Hallucinations, confusion, or mental depression
• Seizures
• Severe drowsiness, especially in elderly patients If any side effects are severe or persistent, consult a doctor.

Precautions

• Abrupt Withdrawal: Do not stop taking BACLOF Liquid suddenly. Abrupt discontinuation can lead to severe withdrawal symptoms, including seizures, confusion, fever, muscle stiffness, or worsening spasticity.
• Central Nervous System (CNS) Depressants: This medicine may cause drowsiness, dizziness, or vision problems. Avoid driving, operating machinery, or performing other tasks requiring alertness until you know how the medicine affects you.
• Alcohol Interaction: Avoid consuming alcohol while taking BACLOF Liquid, as it can increase drowsiness and other CNS depressant effects.
• Medical Conditions: Inform your doctor if you have kidney disease, diabetes, epilepsy (seizures), mental health conditions (e.g., psychosis, schizophrenia), ovarian cysts, a history of stroke, or heart problems. Elderly patients may be more sensitive to the effects of this medicine.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Excipients: Contains sorbitol (E420), which may cause gastrointestinal discomfort or a mild laxative effect.

Storage

Store BACLOF Liquid in the refrigerator and do not freeze. Keep the medicine in a closed container, away from heat, moisture, and direct light, and out of the reach of children. Discard any unused medication after the expiration date or 60 days after first opening, as per product instructions.

BACLOF (STRAWBERRY FLAVOUR) LIQUID 100 ML by INTAS PHARMACEUTICALS LTD. is a muscle relaxant containing Baclofen as its active ingredient. It is primarily used to manage muscle rigidity, tension, stiffness, and spasms associated with various neurological conditions.

Here are some frequently asked questions about BACLOF (STRAWBERRY FLAVOUR) LIQUID:

What is BACLOF Liquid used for?

BACLOF Liquid is used to treat muscle spasms, rigidity, tension, and stiffness caused by conditions affecting the nervous system. These conditions include multiple sclerosis, cerebral palsy, spinal cord injuries, motor neuron disease, and problems arising from head, brain, or spine injuries. It helps relieve pain and improve muscle movement, enhancing daily functioning and quality of life.

How does BACLOF Liquid work?

BACLOF Liquid contains Baclofen, which is a skeletal muscle relaxant. It works by acting on the brain and spinal cord, specifically by activating GABA-B receptors. This action reduces the transmission of nerve messages that cause muscles to contract tightly, thereby inhibiting the release of excitatory neurotransmitters that lead to muscle spasms and rigidity. This results in muscle relaxation, relieving stiffness and improving muscle movement.

What is the usual dosage of BACLOF Liquid?

The dose of BACLOF Liquid will vary depending on the patient's condition and response to treatment. For adults, treatment usually starts with a low dose, such as 5mg (one 5ml spoonful) three times a day for three days, and is gradually increased by the doctor every three days based on clinical response and tolerability. The typical maximum daily dosage for adults is 80 mg (20 mg four times a day). For children, the dosage is determined by the doctor, often starting with a very low dose and gradually increasing it based on body weight. It's crucial to use a specially marked oral syringe or medicine spoon to measure the exact dose.

What are the possible side effects of BACLOF Liquid?

Common side effects can include feeling sleepy, tired, dizzy, or weak, nausea, vomiting, headaches, problems sleeping, dry mouth, rapid eye movements, blurred vision, or difficulty focusing. Serious side effects, though less common, can include allergic reactions (rash, itching, hives, swelling), changes in urination, confusion, seizures, or difficulty breathing. If the dose is too high, muscle weakness can occur.

Is BACLOF Liquid safe during pregnancy or breastfeeding?

Pregnancy: BACLOF is not often recommended during pregnancy. However, a doctor may recommend continuing it if necessary to maintain the mother's health. If taken in later pregnancy, the baby may need monitoring for withdrawal symptoms such as shakiness, seizures, or increased muscle tone after birth. It is important to consult a doctor immediately if you become pregnant while taking this medicine.

Breastfeeding: Limited information suggests that baclofen passes into breast milk in small amounts, and no harmful effects have been reported in breastfed babies. If the baby is healthy, a doctor or health visitor may advise continuing BACLOF while breastfeeding. However, it's recommended to contact a healthcare provider if the baby seems unusually sleepy, is not feeding well, or develops a rash.

Can BACLOF Liquid be taken with other medications?

BACLOF Liquid can interact with other medications, potentially increasing the risk of side effects. It's crucial to inform your doctor about all prescription, over-the-counter, herbal remedies, vitamins, and supplements you are taking. Combining Baclofen with alcohol or other central nervous system (CNS) depressants (such as antihistamines, sedatives, tranquilizers, sleeping medicines, narcotic pain medicines, and other muscle relaxants) can increase drowsiness, dizziness, confusion, and may lead to serious side effects like respiratory depression. Interactions can also occur with antidepressants (e.g., amitriptyline), lithium, and medicines for high blood pressure or Parkinson's disease (levodopa).

What precautions should be taken when using BACLOF Liquid?

• Do not stop suddenly: Do not abruptly stop taking BACLOF Liquid, especially if you have been taking it for a long time or in high doses. Sudden discontinuation can lead to severe withdrawal symptoms such as increased muscle spasms, fever, confusion, hallucinations, and seizures. Your doctor will advise on a gradual dose reduction.
• Drowsiness/Dizziness: BACLOF can cause drowsiness, dizziness, and affect vision or coordination. Avoid driving, operating machinery, or performing tasks that require alertness until you know how the medicine affects you.
• Alcohol: Avoid consuming alcohol as it can increase the sedative effects.
• Medical Conditions: Inform your doctor if you have kidney disease, diabetes, epilepsy, mental illness, ovarian cysts, or a history of stroke, as these conditions may require caution or dose adjustments.
• Administration: Take BACLOF Liquid with or after food or a milk drink to help reduce nausea. Use a measuring spoon or syringe provided by your pharmacist for accurate dosing.

What happens if a dose is missed?

If you miss a dose of BACLOF Liquid, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double or extra dose to make up for a missed one.

How should BACLOF Liquid be stored?

BACLOF Liquid should generally be stored in a closed container at room temperature, away from heat, moisture, and direct light. Some oral liquid formulations of Baclofen may require refrigeration, but should not be frozen. Always check the specific storage instructions on the product label or ask your pharmacist. Keep it out of reach of children.