Macfolate Plus Capsule (10 Cap)

MACFOLATE PLUS CAPSULE (10 CAP) by MACLEODS PHARMACEUTICALS LTD.

MACFOLATE PLUS CAPSULE is a comprehensive dietary supplement formulated to address and prevent various vitamin and mineral deficiencies, supporting overall health and well-being.

Composition Each capsule typically contains a blend of active ingredients:

• L-Methyl Folate (1 mg)
• Methylcobalamin JP (1.5 mg)
• Eicosapentaenoic Acid (EPA) (150 mg)
• Docosahexaenoic Acid (DHA) (100 mg)
• Alpha Lipoic Acid (30 mg)
• Zinc (from Zinc Sulphate Monohydrate IP) (7.5 mg)
• Benfotiamine (150 mg)
• L-Carnitine (50 mg)
• Vitamin D3 (Cholecalciferol) (1000 IU)
• Pyridoxal 5-Phosphate (0.5 mg) Some formulations may also include Omega-6 Fatty Acids and Folic Acid.

Uses Macfolate Plus Capsule is prescribed for various medical conditions and to support bodily functions, including:

• Management and prevention of vitamin and mineral deficiencies.
• Supporting neurological health and nerve function, particularly beneficial for conditions like diabetic neuropathy.
• Boosting cardiovascular health and offering cardioprotective effects.
• Assisting metabolic functions, energy production, and cognitive function.
• Enhancing immune performance, wound healing, and cell growth and division.
• Promoting bone health.
• Contributing to prenatal health by reducing risks of neural tube defects, pregnancy-related anemia, and complications related to elevated homocysteine levels, and may help reduce nausea in pregnancy.
• Dietary management in patients with low red blood cells.

Dosage and Administration The typical dosage is usually one capsule daily, or as directed by a medical practitioner. The capsule should be swallowed whole with a glass of water, without crushing or chewing. It is often recommended to consume it with a meal for better absorption. Do not exceed the prescribed dosage.

Side Effects Macfolate Plus Capsule is generally safe and typically does not cause side effects when taken as recommended. However, some rare and temporary side effects may include:

• Gastrointestinal discomfort (e.g., nausea, stomach upset, diarrhea, bitter taste, vomiting).
• Impaired concentration, irritation, loss of appetite.
• Skin irritation, burning sensation, headache.
• Allergic reactions. If any serious or persistent side effects occur, consult a doctor immediately.

Precautions

• Consult a doctor before use if you have known allergies to any ingredients, existing health conditions, or are taking other medications or supplements.
• Inform your doctor if you have blood disorders like pernicious anemia or malabsorption syndrome.
• For planned surgeries, you may be advised to stop taking the supplement 2-3 weeks prior.
• While generally considered safe, pregnant and breastfeeding women should consult their doctor before taking this supplement.
• Limit alcohol consumption, as it may affect the medicine's effectiveness or exacerbate side effects.
• Use with caution in patients with bleeding disorders or those on blood thinners.
• Dietary supplements are not a substitute for a balanced diet and a healthy lifestyle.

Storage Store Macfolate Plus Capsule in a cool, dry place, ideally at a temperature below 25 degrees Celsius. Protect it from direct sunlight and moisture. Keep out of reach of children and pets.

MACFOLATE PLUS CAPSULE is a dietary supplement containing a blend of essential vitamins, minerals, and fatty acids. It is manufactured by MACLEODS PHARMACEUTICALS LTD..

What is Macfolate Plus Capsule used for?

Macfolate Plus Capsule is primarily used as a dietary supplement to manage or reduce the risk of vitamin and mineral deficiencies and to support overall health and well-being. It contributes to neurological, cardiovascular, metabolic, immune, and bone health, and can also be beneficial for prenatal health and alleviating symptoms of diabetic complications. It is often prescribed for conditions affecting nerve function, such as diabetic neuropathy, and for patients with low red blood cells.

How does Macfolate Plus Capsule work?

Macfolate Plus Capsule works through a combination of its active ingredients. For example, L-Methyl Folate, an active form of folic acid, helps in producing new blood cells and prevents low folate levels, as well as lowering homocysteine levels, which are linked to pregnancy complications. Methylcobalamin (Vitamin B12) supports nerve function, brain health, and red blood cell production. Pyridoxal 5 Phosphate (Vitamin B6) is involved in metabolism, red blood cell formation, and neurotransmitter synthesis. Alpha Lipoic Acid and Benfotiamine are potent antioxidants that protect cells from damage and support nerve function, particularly in diabetic complications. Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) are Omega-3 fatty acids that support brain function, eye health, and cardiovascular health. Vitamin D3 helps in calcium absorption for strong bones, and Zinc plays a key role in immune function, wound healing, and cell growth. L-Carnitine helps convert fat into energy.

What is the usual dosage?

The usual dosage of Macfolate Plus Capsule should be as directed by your doctor. It may vary based on individual factors like the severity of the condition and response to treatment. It is important to follow the prescribed dosage and never exceed it without consulting your doctor. The capsule should be swallowed whole with a glass of water, and it can be taken with or without food, though taking it with a meal may help with better absorption or reduce gastrointestinal discomfort.

What are the possible side effects?

Most side effects are temporary and generally harmless, resolving upon discontinuation of the medicine. However, if any serious side effects occur or worsen, consult your doctor. Common side effects can include gastrointestinal discomfort, nausea, vomiting, diarrhea, headache, loss of appetite, skin rash, or allergic reactions.

Is it safe during pregnancy or breastfeeding?

Macfolate Plus Capsule is generally considered safe for use during pregnancy, with studies showing low or no risk to the developing baby. However, it is always wise to discuss with your doctor before starting this medicine if you are pregnant or planning to conceive. Similarly, while breastfeeding, it is advisable to consult your doctor to assess potential risks and benefits for both you and your baby.

Can it be taken with other medications?

It is advisable to consult your doctor before taking Macfolate Plus Capsule with other medications to avoid potential drug interactions. While some sources indicate no known significant drug-drug interactions, L-methylfolate, one of its components, can interact with certain medications such as capecitabine, carbamazepine, methotrexate, sulfasalazine, and warfarin. Always inform your doctor about all ongoing medications, including over-the-counter products, vitamins, and herbal supplements.

What precautions should be taken?

Before taking Macfolate Plus Capsule, inform your doctor about any existing health conditions, allergies to any of its ingredients, or if you are undergoing any planned surgery. It should be used with caution in patients with bleeding disorders or those taking blood thinners. Do not exceed the recommended dosage. Limit alcohol consumption, as it could impact the effectiveness or exacerbate side effects. Elderly patients may be more susceptible to side effects and should take this medicine under medical supervision.

What happens if a dose is missed?

If you forget to take a dose of Macfolate Plus Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not double the dose to make up for the forgotten dose. Always consult your doctor before making any changes to your dosage.

How should it be stored?

Macfolate Plus Capsule should be stored in a cool, dry place, ideally at a temperature below 25 degrees Celsius (or below 30 degrees Celsius, or at room temperature). Keep it away from direct sunlight and moisture to protect its effectiveness, and always keep the medicine out of reach of children.