Ivabid 5 Tablet

IVABID 5 TABLET

IVABID 5 TABLET is a cardiac medication manufactured by Abbott, primarily used for managing certain heart conditions. It works by slowing the heart rate, thereby reducing the heart's workload and improving its efficiency.

• Name:

  • Brand Name: IVABID 5 TABLET
  • Common Name: Ivabradine

• Composition: IVABID 5 TABLET contains 5 mg of Ivabradine as its active ingredient. Ivabradine is classified as a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker, which acts by selectively inhibiting the "funny" (If) current in the sinoatrial node, the heart's natural pacemaker.

• Uses: IVABID 5 TABLET is prescribed for:

  • Chronic Stable Angina: To manage chest pain (angina pectoris) in adult patients who experience stable angina symptoms and cannot tolerate or take heart medications like beta-blockers, or when beta-blockers alone are insufficient. It helps reduce the frequency and severity of chest pain and improves exercise tolerance.
  • Chronic Heart Failure: To reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure, a reduced left ventricular ejection fraction (≤ 35%), a sinus rhythm with a resting heart rate of ≥ 70 beats per minute, and who are either on maximally tolerated doses of beta-blockers or have a contraindication to beta-blocker use. It improves heart function and reduces symptoms such as fatigue and breathlessness.

• Dosage and Administration: The recommended starting dose for adults is typically 5 mg twice daily, taken with food. The dosage may be adjusted after two weeks by a healthcare professional to achieve a resting heart rate between 50 and 60 beats per minute, based on individual response and tolerability. The maximum dose is 7.5 mg twice daily.

  • Swallow the tablet whole with water. Do not crush, break, or chew.
  • Take the medicine at the same time each day to maintain consistent levels in the body.
  • Do not discontinue the medication abruptly without consulting a doctor.

• Side Effects:

  • Common Side Effects: Headache, dizziness, blurred vision or temporary enhanced brightness/flashes (luminous phenomena/phosphenes), slow heart rate (bradycardia), increased blood pressure, nausea, abdominal pain, diarrhea, and ECG changes.
  • Serious Side Effects: Irregular or rapid heartbeat (atrial fibrillation), very slow heartbeat, fainting, or significant changes to heartbeat that may require urgent medical attention.

• Precautions:

  • IVABID 5 TABLET is generally not recommended during pregnancy or for women planning to become pregnant, and it is considered unsafe during breastfeeding.
  • Avoid alcohol consumption while taking this medicine.
  • Caution is advised in patients with liver or kidney problems, low blood pressure (hypotension), a very slow resting heart rate, or specific heart rhythm disorders.
  • Due to potential dizziness or blurred vision, avoid driving or operating machinery until you know how the medicine affects you.
  • Inform your doctor about all other medications, including herbal and supplement products, as interactions can occur with CYP3A4 inhibitors (e.g., certain antifungals, antibiotics, HIV medicines), other cardiac medicines (e.g., digoxin, amiodarone, beta-blockers), and grapefruit juice.
  • Regular monitoring of heart rate and blood pressure is recommended.
  • Not recommended for use in patients below 18 years of age.

• Storage: Store IVABID 5 TABLET at room temperature, ideally below 30°C or between 10ºC to 25ºC. Protect it from light and moisture. Keep the medicine out of the sight and reach of children. Do not use the medicine after its expiry date.

Here are frequently asked questions about IVABID 5 TABLET by ABBOTT:

What is Ivabid 5 Tablet used for?

Ivabid 5 Tablet is primarily used to treat chronic stable angina (chest pain caused by reduced blood flow to the heart) and chronic heart failure in adult patients. It is prescribed for individuals who cannot tolerate beta-blockers or whose symptoms are not adequately controlled with them, or when beta-blockers are contraindicated.

How does Ivabid 5 Tablet work?

Ivabid 5 Tablet contains Ivabradine, which works by selectively inhibiting the "funny" (If) current in the heart's natural pacemaker, the sinoatrial node. This action slows down the heart rate, reducing the workload on the heart and improving its efficiency in pumping blood and delivering oxygen to the heart muscle.

What is the usual dosage for Ivabid 5 Tablet?

The typical starting dose is 5 mg twice daily, taken with food. Your doctor will determine the appropriate dose based on your condition and heart rate, and it may be adjusted. The maintenance dose should not exceed 7.5 mg twice daily. It's crucial to follow your doctor's instructions and not exceed the prescribed dose.

What are the possible side effects of Ivabid 5 Tablet?

Common side effects include luminous visual phenomena (temporary brightness, flashes, or halos in vision, often in the first two months of treatment), slow heart rate (bradycardia), headache, dizziness, and increased blood pressure. Other reported side effects include nausea, diarrhea, abdominal pain, and blurred vision. Serious but less common side effects can include atrial fibrillation or other significant changes in heartbeat, which require urgent medical attention.

Is Ivabid 5 Tablet safe during pregnancy or breastfeeding?

Ivabid 5 Tablet is considered unsafe for use during pregnancy as it may harm the developing fetus. It is generally not recommended for use while breastfeeding due to a lack of safety information. Women of childbearing potential should use reliable contraception while taking this medication.

Can Ivabid 5 Tablet be taken with other medications?

Certain medications should be avoided or used with caution. You should not take Ivabid 5 Tablet with strong CYP3A4 inhibitors, such as some antifungal medications (e.g., ketoconazole, itraconazole), antibiotics (e.g., clarithromycin), HIV medications (e.g., ritonavir, nelfinavir), and certain heart medicines (e.g., diltiazem, verapamil), as these can increase Ivabid levels and the risk of side effects. Avoid consuming grapefruit juice and St. John's wort while on this medication, as they can also affect how it works. Caution is advised when used with other cardiac medicines like digoxin, beta-blockers, amiodarone, or quinidine, as they can further slow the heart rate.

What precautions should be taken while taking Ivabid 5 Tablet?

Do not take Ivabid 5 Tablet if you have a severe allergy to ivabradine, severe liver problems, very low blood pressure, acute decompensated heart failure, certain heart rhythm disorders (like sick sinus syndrome, third-degree AV block), or if your heart rate is controlled by a pacemaker. Exercise caution if you have mild to moderate liver problems or kidney issues. Since it may cause dizziness or blurred vision, avoid driving or operating machinery until you know how the medicine affects you. Do not stop taking the medication abruptly without consulting your doctor, as it can worsen your condition.

What happens if a dose is missed?

If you miss a dose of Ivabid 5 Tablet and it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

How should Ivabid 5 Tablet be stored?

Ivabid 5 Tablet should be stored at room temperature, ideally below 30°C (or between 20°C to 25°C), and protected from light and moisture. Keep it out of sight and reach of children and pets. Ensure that any unused or expired medication is disposed of properly.