Paxidep Cr 37.5 Mg Tablet (10 Tab)

PAXIDEP CR 37.5 MG TABLET

PAXIDEP CR 37.5 MG TABLET is an antidepressant medication manufactured by Sun Pharma Laboratories Ltd.. "CR" denotes controlled release, meaning the active ingredient is released slowly into the bloodstream.

• Composition: Each tablet contains Paroxetine Hydrochloride Controlled Release equivalent to 37.5 mg of Paroxetine. Paroxetine is a selective serotonin reuptake inhibitor (SSRI).

• Uses: It is primarily prescribed for the treatment of:

  • Major depressive disorder
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder
  • Social anxiety disorder (social phobia)
  • Post-traumatic stress disorder (PTSD)
  • Generalized anxiety disorder (GAD)
  • Premenstrual dysphoric disorder (PMDD)

• Dosage and Administration: Take PAXIDEP CR 37.5 MG TABLET orally, with or without food, preferably in the morning. Do not crush, chew, or cut the tablet. The dosage and duration are determined by a doctor based on the condition. It may take several weeks for the full effects to be felt. Do not stop taking this medicine suddenly, as it can lead to withdrawal symptoms.

• Side Effects: Common side effects include nausea, dizziness, headache, fatigue, dry mouth, insomnia, increased sweating, tremors, nervousness, loss of appetite, and sexual dysfunction (decreased libido, delayed ejaculation, erectile dysfunction). Serious side effects are rare but can include suicidal thoughts, seizures, and serotonin syndrome.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended during pregnancy due to potential fetal harm. Use with caution during breastfeeding, as it may pass into breast milk; however, it is sometimes preferred due to minimal concentration. Consult a doctor.
  • Alcohol: Avoid alcohol consumption as it may worsen side effects.
  • Driving/Operating Machinery: May cause dizziness, confusion, sleepiness, or blurred vision; avoid such activities until you know how the medicine affects you.
  • Medical Conditions: Use with caution in patients with liver, kidney, or heart problems, epilepsy (seizures), diabetes, or glaucoma.
  • Age: Not recommended for children under 18 years due to safety concerns. Use with caution in elderly patients.
  • Drug Interactions: Inform your doctor about all current medications to avoid undesired effects, especially monoamine oxidase inhibitors (MAOIs), thioridazine, and pimozide.

• Storage: Store below 30°C in a cool and dry place, away from sunlight and moisture. Keep out of reach of children.

PAXIDEP CR 37.5 MG TABLET, manufactured by SUN PHARMA LABORATORIES LTD., contains Paroxetine as its active ingredient. It is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI).

Here are some frequently asked questions about PAXIDEP CR 37.5 MG TABLET:

What is PAXIDEP CR 37.5 MG TABLET used for?

PAXIDEP CR 37.5 MG TABLET is primarily used to treat major depressive disorder and various anxiety-related conditions. These include obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder, and generalized anxiety disorder (GAD).

How does PAXIDEP CR 37.5 MG TABLET work?

This medicine works by inhibiting the reuptake of serotonin by nerves in the brain. Serotonin is a chemical messenger that helps regulate mood and communication between brain cells. By increasing the concentration of serotonin in the nerve synapses, PAXIDEP CR 37.5 MG TABLET helps to improve mood and alleviate symptoms of depression and anxiety disorders.

What is the usual dosage for PAXIDEP CR 37.5 MG TABLET?

PAXIDEP CR 37.5 MG TABLET is typically taken once daily, usually in the morning, with or without food. Your doctor will determine the correct dose and duration of treatment based on your medical condition. It's important to swallow the tablet whole and not to crush or chew it. The full therapeutic effect may take several weeks to become noticeable, so it is crucial to continue taking the medication as prescribed. Do not change the dose or stop the medication without consulting your doctor.

What are the possible side effects of PAXIDEP CR 37.5 MG TABLET?

Common side effects may include nausea, dizziness, headache, insomnia (difficulty sleeping), fatigue, dry mouth, loss of appetite, increased sweating, nervousness, tremors, confusion, constipation, and sexual disturbances like decreased libido, delayed ejaculation, or erectile dysfunction. More serious but rare side effects can include severe mood changes, suicidal thoughts (especially in those under 25), seizures, and serotonin syndrome (symptoms include confusion, rapid heartbeat, and fever). If you experience severe or persistent side effects, or a sudden worsening of mood, contact your doctor immediately.

Is PAXIDEP CR 37.5 MG TABLET safe during pregnancy or breastfeeding?

PAXIDEP CR 37.5 MG TABLET is generally not recommended during pregnancy unless considered necessary by your physician, as some studies suggest a small increased risk of cardiovascular malformations in the baby if taken in the first trimester. Taking it in the weeks before delivery can sometimes cause short-term withdrawal symptoms or, rarely, breathing problems in the baby. For breastfeeding, paroxetine passes into breast milk in very small amounts, and most authoritative reviewers consider it one of the preferred antidepressants during breastfeeding, provided the baby is healthy. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can PAXIDEP CR 37.5 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications, including prescription drugs, over-the-counter medicines, and herbal supplements you are taking. PAXIDEP CR 37.5 MG TABLET can interact with certain medications, such as monoamine oxidase inhibitors (MAOIs), increasing the risk of side effects like serotonin syndrome. Concomitant use with drugs like tranylcypromine, selegiline, furazolidone, linezolid, phenelzine, isocarboxazid, and metoclopramide is generally not recommended or requires careful monitoring by a doctor. It may also reduce the effectiveness of tamoxifen.

What precautions should be taken with PAXIDEP CR 37.5 MG TABLET?

Avoid consuming alcohol while taking this medicine as it can worsen side effects. Do not drive or operate machinery if you experience dizziness, confusion, sleepiness, or blurred vision. Inform your doctor if you have liver or kidney problems, seizures, glaucoma, heart disease, diabetes, or a history of bipolar disorder. This medication is not recommended for children and adolescents under 18 years of age. Elderly patients over 65 years should use it with caution as it may lower sodium levels in the blood.

What happens if a dose of PAXIDEP CR 37.5 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Missing doses or suddenly stopping the medication can lead to withdrawal symptoms such as mood changes, irritability, dizziness, confusion, and sleep disturbances.

How should PAXIDEP CR 37.5 MG TABLET be stored?

Store PAXIDEP CR 37.5 MG TABLET in a cool, dry place, away from direct sunlight, typically at room temperature (10ºC to 25ºC or below 30ºC). Keep it out of the reach and sight of children.