Repace 25 Mg Tablet (10 Tab)

REPACE 25 MG TABLET

REPACE 25 MG TABLET is a prescription medicine manufactured by SUN PHARMA LABORATORIES LTD.

• Name:

  • Brand Name: REPACE 25 MG TABLET
  • Common Name: Losartan Potassium

• Composition:

  • Each tablet contains 25 mg of Losartan Potassium, which belongs to a class of drugs called angiotensin II receptor blockers (ARBs). Losartan works by blocking the action of certain natural substances that tighten blood vessels, allowing blood to flow more smoothly and the heart to pump more efficiently.

• Uses: REPACE 25 MG TABLET is prescribed for the treatment and management of several cardiovascular and renal conditions:

  • Hypertension (High Blood Pressure): Helps lower and stabilize blood pressure, reducing strain on the heart and blood vessels.
  • Diabetic Nephropathy: Slows kidney damage in individuals with type 2 diabetes and high blood pressure.
  • Prevention of Heart Attack and Stroke: By lowering blood pressure, it helps reduce the risk of serious cardiovascular complications.
  • Chronic Heart Failure: Used to manage symptoms and improve heart function.
  • Reduction of Stroke Risk: Specifically in patients with high blood pressure and left ventricular hypertrophy (enlargement of the heart's left side).

• Dosage and Administration:

  • The usual starting and maintenance dose is typically 50 mg once daily for most patients, though a 25 mg once daily starting dose may be considered for those with intravascular volume depletion (e.g., on high-dose diuretics).
  • It can be taken with or without food, preferably at the same time each day.
  • Swallow the tablet whole with water.
  • The total daily dose can range from 25 mg to 100 mg, administered once or twice daily.
  • Not recommended for children under 6 years of age.

• Side Effects:

  • Common: Dizziness, tiredness, fatigue, low blood pressure, headache, cough, back pain, stuffy nose, and diarrhea.
  • Serious: Symptoms of high potassium levels (e.g., heart rhythm problems, muscle weakness), allergic reactions (swelling of the face, lips, throat), and signs of kidney problems (e.g., swelling in ankles, feet, hands, sudden weight gain, decreased urine output).

• Precautions:

  • REPACE 25 MG TABLET is highly unsafe and contraindicated during pregnancy, especially in the second and third trimesters, as it can cause serious harm to the unborn baby.
  • Consult a doctor before use during breastfeeding, as it is unknown if the medicine is excreted in human milk.
  • Avoid consuming alcohol, as it may increase the risk of low blood pressure.
  • Do not take potassium supplements or consume high-potassium foods without consulting your doctor.
  • Exercise caution if you have liver or kidney problems; regular monitoring may be required.
  • May cause dizziness or drowsiness; therefore, caution is advised when driving or operating machinery.
  • Inform your doctor about all existing medical conditions and current medications, including over-the-counter drugs, supplements, and herbal preparations, to prevent potential interactions.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Store below 30°C.
  • Keep in the original packaging to protect from sunlight and moisture.

REPACE 25 MG Tablet is a medication primarily used to treat high blood pressure (hypertension). It belongs to a class of drugs called angiotensin II receptor blockers (ARBs).

What is REPACE 25 MG Tablet used for?

REPACE 25 MG Tablet is used to treat high blood pressure (hypertension), which helps prevent future heart attacks and strokes. It is also effective in managing chronic heart failure, protecting kidney function in patients with diabetes (diabetic nephropathy), and reducing the risk of stroke in individuals with high blood pressure and left ventricular hypertrophy (enlargement of the heart's left chamber).

How does REPACE 25 MG Tablet work?

REPACE 25 MG Tablet contains Losartan, an angiotensin receptor blocker (ARB). It works by blocking the action of a natural chemical in the body called angiotensin II, which typically causes blood vessels to tighten. By blocking this action, Losartan relaxes and widens the blood vessels, allowing blood to flow more smoothly and lowering blood pressure. This also helps the heart pump more efficiently.

What is the usual dosage of REPACE 25 MG Tablet?

The usual starting and maintenance dose for most patients is 50 mg once daily. If the blood pressure-lowering effect of 50 mg once daily is insufficient, a dose of 25 mg twice daily may be advised before increasing the dose. For individuals with intravascular volume depletion (e.g., those on high-dose diuretics), a starting dose of 25 mg once daily should be considered. The total daily dose can range from 25 mg to 100 mg, taken once or twice daily. It can be taken with or without food, but it's recommended to take it at the same time each day to help remember.

What are the possible side effects of REPACE 25 MG Tablet?

Common side effects may include dizziness, lightheadedness, fatigue, weakness, low blood pressure (hypotension), increased potassium levels in the blood (hyperkalemia), and low blood sugar levels (hypoglycemia). Other reported side effects include headache, cough, back pain, and sometimes gastrointestinal issues like diarrhea or constipation. If you experience severe or persistent side effects, it is important to consult your doctor.

Is REPACE 25 MG Tablet safe during pregnancy or breastfeeding?

REPACE 25 MG Tablet is considered highly unsafe and is not recommended during pregnancy, especially in the second and third trimesters, as it may cause significant harm or even death to the developing baby. It is also generally not recommended during breastfeeding as it is unknown if it passes into breast milk and could potentially harm the nursing infant. Consult your doctor for safe alternatives if you are pregnant or breastfeeding.

Can REPACE 25 MG Tablet be taken with other medications?

REPACE 25 MG Tablet can interact with certain medications. It's important to inform your doctor about all medicines, supplements, or herbal preparations you are taking. Caution is advised with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, diuretics (e.g., hydrochlorothiazide, furosemide), potassium-sparing diuretics (e.g., spironolactone), lithium, and other antihypertensives. Avoid taking potassium supplements or potassium-rich foods, as it may increase potassium levels in your blood.

What precautions should be taken?

Avoid consuming alcohol while taking REPACE 25 MG Tablet, as it can increase the risk of low blood pressure and dizziness. The medicine can cause dizziness, especially during the first few days, so caution is advised when driving or operating machinery. Regular monitoring of kidney function, blood pressure, and potassium levels in the blood is recommended. If you have a history of liver or kidney disease, heart failure, or diabetes, inform your doctor. Do not stop taking the medicine suddenly without consulting your doctor.

What happens if a dose is missed?

If you miss a dose of REPACE 25 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should REPACE 25 MG Tablet be stored?

REPACE 25 MG Tablet should be stored in a cool and dry place, away from direct sunlight and moisture, preferably below 30°C. Keep it in its original packaging and out of sight and reach of children.