Vilatin M50/1000

VILATIN M50/1000

VILATIN M50/1000 is an oral antidiabetic medication manufactured by Ajanta Pharma Limited, used for the management of type 2 diabetes mellitus.

• Name:
  • Brand Name: Vilatin M 50/1000 Tablet
• Composition:
  • Each tablet contains Vildagliptin 50 mg and Metformin 1000 mg.
  • Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin secretion and reduces glucagon levels in a glucose-dependent manner. Metformin is a biguanide that reduces glucose production by the liver, decreases intestinal absorption of glucose, and enhances insulin sensitivity.
• Uses:
  • VILATIN M50/1000 is prescribed to manage high blood sugar levels in adult patients with type 2 diabetes mellitus.
  • It is typically used when diet and exercise alone, or treatment with either metformin or vildagliptin alone, is insufficient to control blood glucose.
  • This medicine also aids in reducing the risk of serious diabetes-related complications such as kidney damage, blindness, nerve problems, limb amputations, and cardiovascular events.
• Dosage and Administration:
  • The typical starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects.
  • The tablet should be swallowed whole with a glass of water; it should not be split, crushed, or chewed.
  • It is crucial to take this medicine regularly at the same time each day as prescribed by your doctor and not to stop the treatment without consultation.
• Side Effects:
  • Common Side Effects: Headache, dizziness, nausea, fatigue, constipation, vomiting, low blood sugar (hypoglycemia), diarrhea, stomach pain, and changes in taste.
  • Serious Side Effects: Rare but serious side effects include lactic acidosis (symptoms like stomach pain, rapid breathing, and sleepiness) and a serious skin reaction called bullous pemphigoid.
• Precautions:
  • Do not use if you are allergic to vildagliptin, metformin, or other ingredients.
  • Contraindicated in patients with severe kidney disease, metabolic acidosis (including diabetic ketoacidosis), severe liver disease, type 1 diabetes, or uncontrolled diabetes with severe symptoms.
  • Avoid excessive alcohol consumption as it increases the risk of lactic acidosis.
  • Consult your doctor if you are pregnant, planning to conceive, or breastfeeding, as caution is advised.
  • Inform your doctor about all other medications you are taking, including antidiabetic medicines, antihypertensives, heart medicines, painkillers, carbonic anhydrase inhibitors, hyperglycemic medications, and ACE-inhibitors, to avoid potential interactions.
  • Regular monitoring of blood sugar and kidney function is essential during treatment.
• Storage:
  • Store VILATIN M50/1000 in a cool and dry place, protected from direct sunlight, moisture, and heat.
  • Keep it out of the sight and reach of children and pets.

Here are frequently asked questions about VILATIN M50/1000 by AJANTA PHARMA LIMITED:

What is VILATIN M50/1000 used for?

VILATIN M50/1000 is primarily used to manage high blood sugar levels in adults with Type 2 diabetes mellitus. It is typically prescribed when diet and exercise alone, or treatment with either metformin or vildagliptin by itself, are not enough to control blood sugar. This medication also helps reduce the risk of serious diabetes complications such as kidney damage, blindness, nerve problems, and cardiovascular events.

How does VILATIN M50/1000 work?

VILATIN M50/1000 contains two active ingredients: Vildagliptin (50 mg) and Metformin (1000 mg). Vildagliptin is a DPP-4 inhibitor that increases the release of insulin from the pancreas and decreases hormones that raise blood sugar, acting only when glucose levels are high. Metformin is a biguanide that reduces glucose production by the liver, decreases glucose absorption from the intestines, and improves the body's sensitivity to insulin. Together, these actions help to control blood sugar levels.

What is the usual dosage for VILATIN M50/1000?

The typical starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. Your doctor will determine the appropriate dosage and frequency based on your condition and blood sugar levels. It is important not to exceed the maximum recommended daily dose, which is generally two tablets per day. The tablet should be swallowed whole with water and not crushed, split, or chewed.

What are the possible side effects of VILATIN M50/1000?

Common side effects may include headache, dizziness, nausea, vomiting, diarrhea, stomach pain, constipation, fatigue, and low blood pressure. Low blood sugar (hypoglycemia) can occur, especially if taken with other diabetes medications like insulin or sulfonylurea. A rare but serious side effect is lactic acidosis, characterized by symptoms such as stomach discomfort, decreased appetite, rapid breathing, muscle pain, and sleepiness. If you experience severe or persistent side effects, consult your doctor.

Is VILATIN M50/1000 safe during pregnancy or breastfeeding?

VILATIN M50/1000 is generally not recommended during pregnancy as there is limited information regarding its safety, and animal studies have shown potential harmful effects on the developing baby. It is also not recommended for breastfeeding women, as its components are known to pass into breast milk. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can VILATIN M50/1000 be taken with other medications?

VILATIN M50/1000 can interact with certain medications. These include some cationic medications (e.g., amiloride, digoxin, morphine), carbonic anhydrase inhibitors (e.g., topiramate), hyperglycemic medications (e.g., glucocorticoids, beta-2-agonists, diuretics), and ACE-inhibitors. It is crucial to inform your doctor about all prescription and over-the-counter medications, supplements, and herbal products you are taking to avoid potential drug interactions.

What precautions should be taken while on VILATIN M50/1000?

You should avoid excessive alcohol consumption while taking VILATIN M50/1000, as it can increase the risk of lactic acidosis. Inform your doctor if you have a history of kidney, liver, or heart disease, pancreatitis, or vitamin B12 deficiency, as these conditions may require caution or dosage adjustments. This medicine is not for Type 1 diabetes or diabetic ketoacidosis. Regular monitoring of blood sugar, kidney, and liver function is essential during treatment. It is also not intended for use in children under 18 years of age.

What happens if a dose of VILATIN M50/1000 is missed?

If you miss a dose of VILATIN M50/1000, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should VILATIN M50/1000 be stored?

VILATIN M50/1000 should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. The recommended storage temperature is below 30°C or 25°C. Keep this medicine out of the sight and reach of children and pets.