Lobg Tablet (10 Tab)

LOBG TABLET (10 TAB) by GLENMARK PHARMACEUTICALS LTD.

• Name:

  • Brand Name: LOBG TABLET
  • Common Name: Lobeglitazone (as Lobeglitazone sulphate)

• Composition:

  • Active Ingredient: Lobeglitazone sulphate 0.5 mg

• Uses: LOBG Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is particularly used in patients whose blood sugar levels are not adequately controlled by diet and exercise alone, or when other anti-diabetic medications are inappropriate. As an insulin sensitizer, it helps improve the body's response to insulin, thereby reducing blood sugar levels and lowering HbA1c levels. This helps prevent serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs.

• Dosage and Administration: LOBG Tablet should be taken exactly as prescribed by your doctor. It can be taken with or without food, preferably at the same time each day to maximize its benefits. Swallow the tablet whole with a glass of water; do not chew, crush, or break it. Your doctor will determine the appropriate dose and duration of treatment based on your age, body weight, and medical condition. It is important not to stop taking the medication without consulting your doctor, as this could lead to a rise in blood sugar levels.

• Side Effects:

  • Common Side Effects:
    • Weight gain
    • Oedema (swelling, especially in extremities)
    • Fatigue
    • Headache These common side effects are usually mild and may resolve over time. However, if they persist or worsen, consult your doctor.

• Precautions:

  • Inform your doctor if you are allergic to Lobeglitazone sulphate or any other medications.
  • Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
  • LOBG Tablet should be used with caution in patients with a history of heart disease, especially heart failure, as it can worsen this condition.
  • Patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, or severe kidney or liver disease should generally not take this medication.
  • Monitor blood sugar levels regularly, particularly in the initial weeks of treatment, and your doctor may recommend blood tests to monitor blood cell counts and liver function.
  • Be aware of symptoms of hypoglycemia (low blood sugar), such as sweating, dizziness, palpitations, and shivering. Carry sugary food or fruit juice to counteract these symptoms if they occur.
  • Limit alcohol consumption as it may increase the risk of side effects.
  • Avoid skipping meals.
  • Drive only if you are alert after taking LOBG Tablet, as some side effects might affect your ability to drive.

• Storage: Store LOBG Tablet in a cool and dry place, away from direct sunlight. The recommended storage temperature is below 30°C, ideally between 20°C to 25°C. Keep it away from moisture, heat, and light, and it should not be frozen. Ensure it is kept out of the reach and sight of children and pets.

What is LOBG TABLET used for?

LOBG TABLET is used to manage type 2 diabetes mellitus in adults, especially when blood sugar levels are not adequately controlled by diet and exercise alone. It helps to control blood sugar levels and can reduce the risk of serious diabetes complications such as kidney damage, eye damage, and nerve problems.

How does LOBG TABLET work?

LOBG TABLET contains Lobeglitazone sulfate, which is an insulin sensitizer. It works by binding to and activating specific receptors (PPAR gamma) within fat cells, making these cells more responsive to insulin. This action helps to lower blood sugar levels, reduce hemoglobin A1C (HbA1C) levels, and can also improve lipid and liver profiles.

What is the usual dosage for LOBG TABLET?

Your doctor will determine the appropriate dose and duration for you, which may be adjusted over time based on your response to the medication. LOBG TABLET should be taken regularly at the same time each day, with or without food. It should be swallowed whole with a glass of water, and not crushed, broken, or chewed.

What are the possible side effects of LOBG TABLET?

Common side effects include edema (swelling in the body) and weight gain. Other potential side effects can include fatigue. More serious, though less common, side effects may include liver damage, heart failure, pancreatitis, bladder cancer, and an increased risk of bone fractures. It's also important to be aware of symptoms of hypoglycemia (low blood sugar), such as sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, and frequent urination.

Is LOBG TABLET safe during pregnancy or breastfeeding?

Limited information is available regarding the use of LOBG TABLET during pregnancy or breastfeeding. It is essential to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medication, as animal studies have shown potential harmful effects on the developing baby.

Can LOBG TABLET be taken with other medications?

LOBG TABLET can be taken alone or in combination with other medicines for type 2 diabetes. It is crucial to inform your doctor about all prescription, non-prescription, and herbal supplements you are currently taking, as LOBG TABLET can interact with various medications. These include other antidiabetic medicines, blood pressure-lowering medicines (e.g., enalapril, losartan), cholesterol-lowering medicines (e.g., atorvastatin, simvastatin), corticosteroids (e.g., prednisone), NSAIDs (e.g., ibuprofen), antifungals (e.g., fluconazole), and certain antibiotics (e.g., rifampin).

What precautions should be taken while taking LOBG TABLET?

LOBG TABLET should not be taken if you have type 1 diabetes mellitus, diabetic ketoacidosis, or severe kidney or liver disease. Inform your doctor if you have a history of heart disease, thyroid disorders, or certain hormonal conditions. Regular monitoring of blood sugar levels is essential, and your doctor may recommend blood tests to monitor blood cell counts and liver function. Avoid alcohol consumption as it may increase the risk of side effects, including low blood sugar. Drive only if you are alert, as the medication may cause dizziness. It is advisable to eat short, frequent meals and avoid prolonged fasting to prevent hypoglycemia, and you should carry sugary food or drinks for such instances. Do not stop taking LOBG TABLET without consulting your doctor, as this can lead to an increase in blood sugar levels.

What happens if a dose of LOBG TABLET is missed?

If you miss a dose of LOBG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should LOBG TABLET be stored?

LOBG TABLET should be stored in a cool and dry place, away from direct sunlight, moisture, and heat. Keep it out of reach and sight of children. It is typically stored at controlled room temperature, between 10°C and 25°C (or below 30°C), and should not be frozen.