Solitral Capsule (10 Cap)

SOLITRAL CAPSULE

Solitral Capsule is a medication manufactured by Sun Pharmaceutical Industries Ltd. used primarily for the treatment of benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms.

Composition

Each Solitral Capsule contains a combination of two active ingredients:

• Alfuzosin: 10 mg
• Solifenacin: 5 mg

Alfuzosin is an alpha-blocker that relaxes the smooth muscles in the prostate and bladder neck, improving urine flow. Solifenacin is an antimuscarinic that inhibits bladder muscle contractions, helping to control the urge to urinate frequently and urgently.

Uses

Solitral Capsule is prescribed for:

• Benign Prostatic Hyperplasia (BPH): It treats the symptoms associated with an enlarged prostate gland in men, such as difficulty passing urine, a strong urge to urinate, and frequent urination.
• Overactive Bladder: It also manages symptoms of an overactive bladder, including sudden, strong urges to urinate and frequent urination.

Dosage and Administration

Follow the dosage and duration as prescribed by your physician.

• Typically, Solitral Capsule is taken once daily.
• It should be swallowed whole with a glass of water; do not crush, chew, or break the capsule.
• It is generally recommended to take this medicine with food for optimal benefits and to reduce stomach upset.
• Do not discontinue the medication abruptly without consulting your doctor.

Side Effects

Common side effects may include:

• Dizziness, headache, tiredness, or weakness
• Dryness in the mouth
• Blurred vision
• Constipation
• Flushing (sense of warmth in the face, ears, neck, and trunk)

Serious side effects, though rare, can include fainting (due to low blood pressure), severe abdominal pain, difficulty urinating, allergic reactions (skin rash, swelling, trouble breathing), and priapism (prolonged painful erection). Seek immediate medical attention if these occur.

Precautions

• Alcohol: Avoid alcohol consumption as it can increase dizziness and drowsiness.
• Driving and Operating Machinery: Due to potential dizziness, blurred vision, or fatigue, avoid driving or operating heavy machinery until you know how the medicine affects you.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking, especially other alpha-blockers or antihypertensive medicines, as interactions can cause a sudden drop in blood pressure.
• Medical Conditions: Inform your doctor if you have kidney or liver disease, heart conditions (like a history of heart attack, stroke, or heart failure), low blood pressure, or certain eye diseases (like glaucoma).
• Specific Populations: This medicine is not recommended for women or children. Elderly patients (65 years or above) should use with caution due to increased sensitivity to side effects like low blood pressure.

Storage

Store Solitral Capsule below 30°C. Keep it away from direct sunlight, heat, moisture, and out of reach of children and pets.

Here are the most frequently asked questions about Solitral Capsule (10 Cap) by Sun Pharmaceutical Ind. Ltd.:

What is Solitral Capsule used for?

Solitral Capsule is primarily used to treat the symptoms of benign prostatic hyperplasia (BPH), also known as an enlarged prostate, in men. It helps to relieve unpleasant urinary symptoms like difficulty in urination, frequent urination, and a sudden, strong urge to urinate. It also addresses symptoms of an overactive bladder.

How does Solitral Capsule work?

Solitral Capsule is a combination of two medicines: Alfuzosin (an alpha-blocker) and Solifenacin (an antimuscarinic). Alfuzosin works by relaxing the smooth muscles in the bladder and prostate gland, which improves urine flow. Solifenacin works by inhibiting the contraction of the smooth muscle wall surrounding the bladder, leading to decreased bladder activity and helping to control urine release, thus reducing urgency and frequency.

What is the usual dosage of Solitral Capsule?

The dosage of Solitral Capsule should be strictly as prescribed by your doctor. It is typically taken once daily, preferably with food, at the same time each day for optimal benefits. Do not chew, crush, or break the capsule; swallow it whole with water.

What are the possible side effects of Solitral Capsule?

Common side effects include dizziness, headache, tiredness, dry mouth, blurred vision, constipation, and flushing (a sense of warmth in the face, ears, neck, and trunk). Serious, though rare, side effects can include severe abdominal pain, difficulty urinating, allergic reactions (swelling of the face, lips, or throat), or priapism (a prolonged, painful erection unrelated to sexual activity). If you experience severe or persistent side effects, contact your doctor.

Is Solitral Capsule safe during pregnancy or breastfeeding?

Solitral Capsule is not intended for use in women or children. It is considered unsafe during pregnancy, and its use during breastfeeding is not recommended due to a lack of available information. Women should not use this medicine as it is specifically for benign prostatic hyperplasia in men.

Can Solitral Capsule be taken with other medications?

Solitral Capsule can interact with several medications. Avoid taking it with other alpha-blockers, certain medicines for high blood pressure (antihypertensives), nitrates, some antifungal medications (e.g., itraconazole, ketoconazole), HIV medications (e.g., ritonavir), and some heart medications (e.g., verapamil, diltiazem). Combining Solitral Capsule with antihypertensive medicines can lead to a sudden and life-threatening drop in blood pressure. Always inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using Solitral Capsule?

Exercise caution when consuming alcohol with Solitral Capsule, as it can increase dizziness and drowsiness. Avoid driving or operating heavy machinery until you know how the medicine affects you, as it may cause dizziness, blurred vision, or tiredness. Inform your doctor if you have kidney, liver, or heart disease, or if you are scheduled for any surgery. Elderly patients (65 years or above) may be more sensitive to side effects like dizziness and low blood pressure.

What happens if a dose of Solitral Capsule is missed?

If you miss a dose of Solitral Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Solitral Capsule be stored?

Solitral Capsule should be stored in a cool and dry place, typically below 30°C. Keep it away from direct sunlight, heat, and moisture, and ensure it is out of the reach of children and pets.