Lipirose 5 Mg Tablet (10 Tab)

LIPIROSE 5 MG TABLET

LIPIROSE 5 MG TABLET is a medication primarily used for managing high cholesterol and reducing the risk of cardiovascular events. It is manufactured by Mankind Pharma Ltd..

• Name:

  • Brand Name: LipiROSE 5 Tablet, Lipirose 5 MG Tablet
  • Common Name: Rosuvastatin Tablets 5 mg

• Composition:

  • Active Ingredient: Rosuvastatin (5 mg)

• Uses: LIPIROSE 5 MG TABLET belongs to a class of medicines called statins. It is prescribed for:

  • Lowering elevated total cholesterol, "bad" cholesterol (LDL-C), non-HDL-C, and triglycerides (TG) levels in the blood.
  • Increasing "good" cholesterol (HDL-C) levels.
  • Treating primary hyperlipidemia, mixed dyslipidemia, hypertriglyceridemia, and primary dysbetalipoproteinemia (Type III hyperlipoproteinemia).
  • Slowing the progression of atherosclerosis (narrowing of blood vessels due to fat buildup).
  • Reducing the risk of major cardiovascular events such as heart attack and stroke.

• Dosage and Administration:

  • Typically taken once daily, with or without food.
  • It is advisable to take the medicine at the same time each day for consistency.
  • Swallow the tablet whole; do not chew, crush, or break it.
  • Dosage is individualized by a doctor based on cholesterol levels and response to medication.
  • For Asian patients, initiation of therapy with 5 mg once daily should be considered.
  • In severe renal impairment (ClCr<30 mL/min/1.73 m²) not on hemodialysis, the dose should be started at 5 mg once daily and not exceed 10 mg once daily.
  • Do not stop taking the medicine without consulting your doctor.

• Side Effects:

  • Common Side Effects: Headache, muscle pain (myalgia), abdominal pain, nausea, weakness (asthenia), constipation, dizziness.
  • Serious Side Effects:
    • Muscle problems like myopathy and rhabdomyolysis (can lead to kidney damage).
    • Liver problems, indicated by stomach pains, unusually dark urine, or yellowing of the skin or eyes.
    • Increase in blood sugar levels.

• Precautions:

  • Contraindications: Do not use if allergic to rosuvastatin or any of its ingredients, in cases of active liver disease, or during pregnancy and breastfeeding.
  • Medical Conditions: Use with caution in patients with kidney disease, diabetes, hypothyroidism, or pre-existing muscle disorders. Inform your doctor if you have a history of stroke with bleeding inside the brain.
  • Alcohol: Caution is advised when consuming alcohol, as it can increase the risk of liver problems and triglyceride levels.
  • Drug Interactions: Inform your doctor about all medicines, supplements, or herbal products you are taking, especially blood thinners (e.g., warfarin, coumarin), immunosuppressants (e.g., cyclosporine), fibrates (e.g., gemfibrozil, fenofibrate), certain antifungals (e.g., ketoconazole, clotrimazole), and anti-HIV medicines (e.g., lopinavir, ritonavir, atazanavir), as these can increase the risk of side effects or alter the medicine's action.
  • Monitoring: Regular monitoring of cholesterol levels and liver function tests is recommended.
  • Lifestyle: Adhere to a healthy, low-fat diet, regular exercise, and avoid smoking for optimal results.

• Storage:

  • Store below 30°C.
  • Protect from light and moisture.
  • Keep out of the reach of children.

Here are the most frequently asked questions about Lipirose 5 MG Tablet, along with their concise answers:

What is Lipirose 5 MG Tablet used for?

Lipirose 5 MG Tablet is primarily used to lower high cholesterol levels (LDL, or "bad" cholesterol) and triglycerides in adults. It also helps to increase levels of HDL, or "good" cholesterol. By doing so, it reduces the risk of serious heart-related complications such as heart attack and stroke, and slows down the progression of atherosclerosis (narrowing of blood vessels due to fat buildup).

How does Lipirose 5 MG Tablet work?

Lipirose 5 MG Tablet contains rosuvastatin, which belongs to a class of medicines called statins. It works by blocking an enzyme in the liver called HMG-CoA reductase, which is essential for cholesterol production. By inhibiting this enzyme, rosuvastatin reduces the amount of LDL cholesterol in the blood and enhances the liver's ability to remove existing LDL cholesterol, while also increasing HDL cholesterol levels.

What is the usual dosage for Lipirose 5 MG Tablet?

Lipirose 5 MG Tablet should be taken exactly as prescribed by your doctor. The dosage is individualized based on your condition and response to treatment. Typically, it is taken once daily, with or without food, preferably at the same time each day to maintain consistent levels in your body. It is important not to exceed the prescribed dosage.

What are the possible side effects of Lipirose 5 MG Tablet?

Common side effects may include headache, muscle pain (myalgia), abdominal pain, weakness, nausea, fatigue (asthenia), constipation, and dizziness. These side effects are usually mild and temporary. If you experience serious side effects or if common side effects persist or worsen, such as unexplained muscle pain, tenderness, weakness, or yellowing of the eyes/skin, you should consult your doctor immediately.

Is Lipirose 5 MG Tablet safe during pregnancy or breastfeeding?

No, Lipirose 5 MG Tablet is considered unsafe and is contraindicated during pregnancy as it may harm the developing fetus. It is also not recommended for women who are breastfeeding, as it may pass into breast milk and pose risks to the infant. Women of childbearing age should use effective contraception while taking this medicine.

Can Lipirose 5 MG Tablet be taken with other medications?

Lipirose 5 MG Tablet can interact with several other medications, potentially increasing the risk of side effects like muscle damage. These include immunosuppressants (e.g., cyclosporine), fibrates (e.g., gemfibrozil, fenofibrate), certain azole antifungals, some anti-HIV medications (e.g., ritonavir, lopinavir, atazanavir), and niacin. It's crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions. Avoid consuming large amounts of grapefruit juice while on this medication as it can increase its concentration in your blood.

What precautions should be taken while taking Lipirose 5 MG Tablet?

You should inform your doctor if you have any pre-existing medical conditions, especially liver disease, kidney disease, diabetes, hypothyroidism, or a history of muscle disorders, as these can increase the risk of side effects. Regular monitoring of liver enzyme levels is often recommended during treatment. Caution is also advised regarding alcohol consumption, as it may increase the risk of liver damage.

What happens if a dose of Lipirose 5 MG Tablet is missed?

If you miss a dose of Lipirose 5 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Lipirose 5 MG Tablet be stored?

Lipirose 5 MG Tablet should be stored below 30°C. It should be kept in a cool, dry place, protected from direct sunlight and moisture, and out of the reach of children.