Brevipil 75 Mg Tablet (10 Tab)

BREVIPIL 75 MG TABLET

BREVIPIL 75 MG TABLET is an anti-epileptic medication manufactured by SUN PHARMA LABORATORIES LTD. It is primarily used to manage seizures associated with epilepsy.

• Name

  • Brand Name: BREVIPIL 75 MG TABLET
  • Generic Name: Brivaracetam

• Composition

  • Each tablet contains Brivaracetam 75 mg as the active ingredient.

• Uses BREVIPIL 75 MG TABLET is prescribed for the treatment of epilepsy, specifically for partial-onset seizures (also known as focal seizures) in adults and children aged 1 month and older. It can be used alone (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) to help control seizures. This medicine works by reducing abnormal electrical impulses and excessive nerve activity in the brain that trigger seizures.

• Dosage and Administration BREVIPIL 75 MG TABLET should be taken orally, swallowed whole with liquid, and should not be crushed, chewed, or broken. It can be taken with or without food, preferably at the same time each day for optimal results. The dosage and frequency are determined by the healthcare provider based on factors such as age, weight, and medical condition, and may be gradually adjusted. For adults, a usual starting dose may be 50 mg twice daily, with a maximum recommended dose up to 200 mg twice daily. For children, the dosage is based on body weight. It is crucial to adhere to the prescribed regimen, as abrupt discontinuation can worsen seizure activity.

• Side Effects Common side effects may include:

  • Drowsiness, excessive sleepiness (somnolence), fatigue, overtiredness, lethargy
  • Dizziness, vertigo (spinning sensation), balance disorder
  • Nausea, vomiting, constipation
  • Headache
  • Behavioral changes, agitation, aggressive behavior, irritation, anxiety, depression, restlessness, difficulty sleeping (insomnia)

  Serious side effects, though rare, can include thoughts of harming or killing oneself. Patients should report any persistent or worsening side effects to their doctor.

• Precautions

  • Pregnancy and Breastfeeding: Use with caution during pregnancy; consult a doctor. Breastfeeding is not recommended unless advised by a doctor.
  • Alcohol: Avoid alcohol consumption during treatment as it can increase side effects like dizziness and drowsiness.
  • Driving and Operating Machinery: Due to potential drowsiness, dizziness, and fatigue, avoid driving or operating heavy machinery until you know how the medicine affects you.
  • Medical Conditions: Inform your doctor about any existing liver or kidney issues, depression, or suicidal tendencies. Dose adjustments may be necessary for patients with liver or kidney impairment.
  • Abrupt Withdrawal: Do not stop taking BREVIPIL 75 MG TABLET suddenly without medical supervision, as it can worsen seizures or lead to increased frequency of fits.

• Storage Store BREVIPIL 75 MG TABLET in a cool and dry place, away from direct sunlight and out of the sight and reach of children. Recommended storage temperatures typically range from 10ºC to 25ºC or below 30ºC.

What is BREVIPIL 75 MG TABLET used for?

BREVIPIL 75 MG TABLET is an anti-epileptic medication primarily used to treat partial-onset seizures in individuals with epilepsy, in patients one month of age and older. It can be used alone (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) to help control seizures.

How does BREVIPIL 75 MG TABLET work?

The active ingredient in BREVIPIL, Brivaracetam, works by binding to a specific site called synaptic vesicle protein 2A (SV2A) on the surfaces of nerve cells in the brain. This action helps to suppress abnormal electrical activity of nerve cells and prevents the spread of electrical signals that cause seizures.

What is the usual dosage for BREVIPIL 75 MG TABLET?

For adults and children 16 years of age and older, the typical starting dose is 50 mg twice daily. The dosage may be adjusted by a healthcare professional based on individual response and tolerability, up to a maximum recommended dose of 100 mg twice daily. For children aged 1 month to less than 16 years, the dosage is determined based on their body weight. It is generally advised to take the tablet whole with or without food, at the same time every day, to maintain consistent levels in the body.

What are the possible side effects of BREVIPIL 75 MG TABLET?

Common side effects can include dizziness, headache, nausea, vomiting, fatigue, and drowsiness. Behavioral changes such as agitation, aggressive behavior, or irritability may also occur. More serious, but rare, side effects can include suicidal thoughts or actions, and serious allergic reactions like bronchospasm and angioedema. Most common side effects are more frequent during the first few weeks and usually lessen as your body adjusts to the medicine.

Is BREVIPIL 75 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: Limited data is available regarding the use of BREVIPIL during pregnancy. Animal studies have shown potential harm to a developing fetus, including decreased growth. BREVIPIL should only be used during pregnancy if clearly necessary and if the potential benefits outweigh the risks. Patients who become pregnant while on this medication are encouraged to enroll in a pregnancy registry.

Breastfeeding: Brivaracetam is excreted into human milk. The effects of the drug on a breastfed infant are not fully known. It is generally recommended to discuss the potential risks and benefits with your doctor. Some sources suggest monitoring the infant for drowsiness, agitation, and adequate weight gain, while others advise considering an alternative medication or avoiding breastfeeding during treatment.

Can BREVIPIL 75 MG TABLET be taken with other medications?

Yes, BREVIPIL can be used alone or in combination with other antiepileptic drugs. However, it's important to inform your doctor about all medications, supplements, and herbal products you are taking, as some interactions can occur:

• Carbamazepine and Phenytoin: Co-administration may affect the levels of these drugs or their metabolites.
• Rifampicin: May decrease the effectiveness of BREVIPIL, potentially requiring a dose adjustment (e.g., doubling the dosage of BREVIPIL).
• St. John's Wort: May interfere with the effectiveness of BREVIPIL.
• Levetiracetam: While both bind to SV2A, using Brivaracetam with Levetiracetam does not provide additional therapeutic benefit.
• Alcohol: Concomitant use with alcohol should be avoided or limited as it can increase side effects such as drowsiness and dizziness.

What precautions should be taken while taking BREVIPIL 75 MG TABLET?

Do not stop taking BREVIPIL suddenly without consulting your doctor, as abrupt discontinuation can worsen seizures or lead to severe complications. Avoid driving or operating heavy machinery until you understand how the medicine affects you, as it can cause drowsiness, dizziness, and coordination problems. Inform your doctor if you have a history of liver disease, kidney disease, mood disorders, depression, or suicidal thoughts.

What happens if a dose of BREVIPIL 75 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose (typically within 3-4 hours), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should BREVIPIL 75 MG TABLET be stored?

Store BREVIPIL 75 MG TABLET in a cool, dry place, typically below 25°C or 30°C. Keep it in its original packaging to protect it from light and moisture. Ensure it is kept out of the reach of children and pets.