Natrilam 1.5/10 Mg

NATRILAM 1.5/10 MG by SERDIA PHARMACEUTICALS (INDIA) PVT. LTD.

Name

• Brand Name: NATRILAM 1.5/10 MG
• Common Name: Amlodipine and Indapamide (combination)

Composition NATRILAM 1.5/10 MG contains two active ingredients:

• Amlodipine 10 mg
• Indapamide 1.5 mg

Uses NATRILAM 1.5/10 MG is primarily prescribed for the management of hypertension (high blood pressure). It helps to effectively control blood pressure, especially when single-medication treatments are not sufficient. By lowering blood pressure, it also reduces the risk of serious cardiovascular events such as stroke and heart attack. Additionally, it aids in controlling fluid retention and edema, promotes vasodilation to improve blood flow, and supports kidney function in patients with hypertension.

Dosage and Administration NATRILAM 1.5/10 MG should be taken as directed by your doctor. It is typically administered orally once daily, preferably in the morning, with or without food. The tablet should be swallowed whole and not crushed, chewed, or broken. Do not discontinue the medication without consulting your doctor.

Side Effects Common side effects may include headache, dizziness, nausea, stomach pain, tiredness, visual disturbances, muscle cramps, diarrhea, constipation, indigestion, increased heart rate, flushing (skin redness), and ankle swelling (oedema). It may also lead to reduced levels of potassium in the blood.

Serious side effects, though rare, warrant immediate medical attention. These include severe skin reactions (such as Stevens-Johnson syndrome or toxic epidermal necrolysis), heart attack, irregular heartbeat, signs of an inflamed pancreas (severe stomach and back pain), sudden chest pain, wheezing, and trouble breathing.

Precautions

• Pregnancy and Breastfeeding: NATRILAM 1.5/10 MG is generally not recommended during pregnancy or breastfeeding.
• Medical Conditions: Inform your doctor if you have kidney disease (especially severe), liver problems, heart conditions (e.g., heart failure, recent heart attack, severe aortic stenosis), diabetes, gout, low blood pressure, or low potassium levels (hypokalaemia).
• Alcohol: Avoid alcohol consumption while taking this medicine, as it can lower blood pressure and increase certain side effects.
• Driving and Machinery: This medicine may cause dizziness or tiredness. Exercise caution when driving or operating machinery until you know how it affects you.
• Drug Interactions: Inform your doctor about all other medications you are taking, including over-the-counter and herbal products, as interactions can occur. Avoid consuming grapefruit or grapefruit juice, as it may interact with Amlodipine and increase the risk of side effects.
• Pediatric Use: NATRILAM 1.5/10 MG is not recommended for use in children under 18 years of age.

Storage Store NATRILAM 1.5/10 MG in a cool, dry place, away from direct sunlight, at a temperature below 30°C. Keep the tablets in their original packaging to protect them from moisture and ensure they are out of the sight and reach of children.

What is NATRILAM 1.5/10 MG used for?

NATRILAM 1.5/10 MG is primarily used to manage high blood pressure, also known as hypertension. It is a combination medicine prescribed especially when high blood pressure is not adequately controlled by either amlodipine or indapamide alone. Managing hypertension helps reduce the risk of serious health complications such as heart disease, kidney disease, stroke, and heart attack.

How does NATRILAM 1.5/10 MG work?

NATRILAM 1.5/10 MG contains two active ingredients: Amlodipine and Indapamide. Amlodipine is a calcium channel blocker that works by relaxing the blood vessels, which allows blood to flow through them more easily and lowers blood pressure. Indapamide is a thiazide-like diuretic that helps reduce blood pressure by increasing the amount of urine produced by the kidneys, thereby promoting the excretion of excess fluid and certain salts (like sodium) from the body.

What is the usual dosage for NATRILAM 1.5/10 MG?

The usual dosage for NATRILAM 1.5/10 MG is one tablet once daily. It is generally recommended to take the tablet in the morning with water, with or without food. It should be swallowed whole and not crushed, chewed, or broken. Always follow your doctor's instructions strictly regarding the dosage and duration.

What are the possible side effects of NATRILAM 1.5/10 MG?

Common side effects of NATRILAM 1.5/10 MG include headache, dizziness, nausea, stomach pain, visual disturbances, muscle cramps, diarrhea, constipation, indigestion, increased heart rate, flushing (skin redness), weakness, tiredness, and swelling in hands, feet, or ankles (oedema). It may also lead to reduced levels of potassium in the blood. If you experience severe side effects or if common side effects persist or worsen, consult your doctor.

Is NATRILAM 1.5/10 MG safe during pregnancy or breastfeeding?

NATRILAM 1.5/10 MG is generally not recommended for use during pregnancy, especially in the second and third trimesters, as animal studies have shown harmful effects on the developing baby. There is also insufficient information on the excretion of Indapamide and Amlodipine in human breast milk, and thiazide diuretics (like Indapamide) have been associated with a decrease in milk production. Therefore, it is contraindicated or not recommended for breastfeeding women. Always consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding.

Can NATRILAM 1.5/10 MG be taken with other medications?

It is crucial to inform your doctor about all other medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, as NATRILAM 1.5/10 MG can interact with certain medicines. For example, concurrent use with ACE inhibitors is not recommended in some circumstances, and grapefruit or grapefruit juice should be avoided as it can increase the level of amlodipine in the blood, potentially enhancing its blood pressure-lowering effects. Your doctor will assess potential drug-drug interactions.

What precautions should be taken while using NATRILAM 1.5/10 MG?

Several precautions should be taken when using NATRILAM 1.5/10 MG:

• Kidney and Liver Conditions: Use with caution in patients with kidney or liver disease, and it is not recommended for those with severe kidney or liver dysfunction.
• Driving and Machinery: This medicine may cause dizziness or tiredness due to low blood pressure, so exercise caution when driving or operating heavy machinery until you know how it affects you.
• Alcohol: Consumption of alcohol is not recommended during treatment with NATRILAM 1.5/10 MG as it can lower blood pressure further and increase side effects like dizziness.
• Other Conditions: Inform your doctor if you have conditions such as diabetes, low blood pressure (hypotension), gout, low potassium levels in the blood (hypokalaemia), or certain heart conditions like severe aortic stenosis.
• Sudden Stoppage: Do not stop taking the medicine abruptly without consulting your doctor, as this can worsen your condition and increase the risk of heart attack or a relapse of high blood pressure.

What happens if a dose is missed?

If you miss a dose of NATRILAM 1.5/10 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects.

How should NATRILAM 1.5/10 MG be stored?

NATRILAM 1.5/10 MG should be stored in a cool, dry place, away from direct sunlight. The ideal storage temperature is typically below 30°C (86°F). Keep the tablets in their original packaging to protect them from moisture and ensure the medicine is kept out of reach of children.