Lipicard Av Tablet ( 10 Tablet )

LIPICARD AV TABLET is a combination medication primarily used to manage abnormal lipid levels in the blood, effectively reducing the risk of cardiovascular diseases such as heart attacks and strokes.

Name

• Brand Name: LIPICARD AV TABLET
• Common Name: Atorvastatin and Fenofibrate Tablets

Composition LIPICARD AV TABLET contains two active ingredients:

• Atorvastatin (10 mg)
• Fenofibrate (160 mg)

Uses This medicine is prescribed for:

• Hyperlipidemia (high lipid levels)
• Mixed dyslipidemia (low good cholesterol and high bad cholesterol and triglycerides)
• Hypercholesterolemia (high cholesterol)
• Hypertriglyceridemia (high levels of triglycerides)
• Prevention of heart diseases and blood vessel blockage (atherosclerosis)

Dosage and Administration LIPICARD AV TABLET is typically taken once daily. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent blood levels. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. Dosage may vary based on individual health conditions and response to medication, as prescribed by a healthcare provider.

Side Effects Common side effects may include:

• Headache
• Muscle pain (myalgia)
• Abdominal/stomach pain
• Nausea
• Constipation
• Diarrhea
• Elevated liver enzymes
• Joint pain (arthralgia)

Serious side effects, though rare, may include:

• Severe allergic reactions
• Unexplained muscle pain or weakness, potentially with fever or reddish-brown urine (rhabdomyolysis)
• Liver damage
• Increased creatinine levels (indicating kidney damage)

Precautions

• Allergies: Do not take if allergic to atorvastatin, fenofibrate, or any other components.
• Liver/Kidney Conditions: Use with caution in patients with kidney disease and is not recommended for those with severe liver or gall bladder problems. Regular monitoring of liver and kidney function is crucial.
• Pregnancy and Breastfeeding: Contraindicated during pregnancy and generally considered unsafe during breastfeeding. Women of childbearing potential should use appropriate contraception.
• Alcohol Consumption: Avoid or limit alcohol intake as it can raise triglyceride levels and increase the risk of liver damage.
• Muscle Disorders: Inform your doctor if you have a history of muscle problems, hypothyroidism, or a family history of such issues, as this medicine may increase the risk of muscle problems.
• Drug Interactions: Inform your doctor about all medications you are taking, especially anticoagulants (e.g., Warfarin), potent CYP3A4 inhibitors (e.g., itraconazole), bile acid sequestrants, and Fusidic acid.

Storage Store LIPICARD AV TABLET in a cool and dry place, protected from direct sunlight and moisture, ideally below 30°C or between 20°C-25°C. Keep it out of sight and reach of children and pets. Store in its original packaging with the desiccant if provided.

What is Lipicard AV Tablet used for?

Lipicard AV Tablet is a combination medication primarily used to manage high cholesterol and triglyceride levels in the blood. It helps reduce the risk of cardiovascular diseases such as heart attacks and strokes, particularly in individuals with hyperlipidemia (high lipid levels), mixed dyslipidemia, hypercholesterolemia, and severe hypertriglyceridemia. It is also used to prevent heart-related issues in adults with type 2 diabetes and at least one cardiovascular risk factor.

How does Lipicard AV Tablet work?

Lipicard AV Tablet contains two active ingredients: Atorvastatin and Fenofibrate.

• Atorvastatin is a statin that works by inhibiting an enzyme called HMG-CoA reductase in the liver, which is crucial for cholesterol production. This action effectively reduces levels of "bad" cholesterol (LDL) and total cholesterol, and triglycerides, while increasing "good" cholesterol (HDL).
• Fenofibrate is a fibric acid derivative that activates a receptor known as PPARα, increasing the breakdown of fats (lipolysis) and helping to eliminate triglyceride-rich particles from the blood. It reduces triglycerides and alters LDL composition, also contributing to an increase in HDL cholesterol. Together, these components work to lower harmful lipid levels, prevent plaque buildup in arteries, and reduce the chances of heart attack and stroke.

What is the usual dosage for Lipicard AV Tablet?

The usual dosage for Lipicard AV Tablet is typically once daily, or as prescribed by your healthcare provider. It should be taken at the same time each day to maintain consistent blood levels. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. It can be taken with or without food, though some sources suggest taking it with meals to improve absorption and reduce stomach upset for fenofibrate. Your doctor will determine the appropriate dose based on your medical condition and response to the medication.

What are the possible side effects of Lipicard AV Tablet?

Common side effects of Lipicard AV Tablet may include muscle pain or weakness (myalgia), headache, abdominal discomfort or pain, nausea, diarrhea, back pain, and elevated liver enzymes. Other reported side effects include constipation, increased blood glucose levels, arthralgia (joint pain), nasopharyngitis, and insomnia.

Serious side effects, though rare, require immediate medical attention and can include severe unexplained muscle pain or weakness with fever or reddish-brown urine (rhabdomyolysis), yellowing of the skin or eyes (jaundice) indicating liver problems, severe allergic reactions (skin rash, blistering, swelling of face/throat, difficulty breathing), unexpected bleeding or bruising, and chest pain, shortness of breath, or irregular heartbeat.

Is Lipicard AV Tablet safe during pregnancy or breastfeeding?

Lipicard AV Tablet is contraindicated (not recommended) for use during pregnancy as it may harm the fetus. Women of childbearing potential should use suitable contraceptive methods to avoid pregnancy while undergoing therapy with this medicine. It is also contraindicated for breastfeeding women, as its active ingredients can pass into breast milk and potentially affect the nursing infant. Consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding.

Can Lipicard AV Tablet be taken with other medications or alcohol?

Lipicard AV Tablet can interact with other medications and alcohol.

• Medication Interactions: Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements. Specific interactions include:
  • Anticoagulants (e.g., Warfarin): May increase the risk of bleeding.
  • Potent CYP3A4 inhibitors (e.g., itraconazole, ketoconazole, HIV protease inhibitors, erythromycin, clarithromycin, telithromycin, nefazodone): May increase the risk of muscle problems when taken with Lipicard AV Tablet.
  • Bile acid sequestrants (e.g., colestipol, cholestyramine): Can affect the absorption of fenofibrate; administer them at least 4 hours apart.
  • Other fibrates (e.g., Gemfibrozil) or Niacin: May increase the risk of muscle damage and kidney problems.
  • Cyclosporine and Colchicine: May increase their levels, leading to toxic effects.
• Alcohol Interaction: Avoid drinking large amounts of alcohol while taking Lipicard AV Tablet as it can increase triglyceride levels and raise the risk of liver damage.

What precautions should be taken while taking Lipicard AV Tablet?

Several precautions should be taken:

• Liver and Kidney Function: Inform your doctor if you have liver or kidney problems. The medicine is not recommended for severe liver or gallbladder issues and should be used with caution in other liver/kidney conditions, often requiring regular monitoring and possible dosage adjustments.
• Muscle Pain: Be aware of symptoms like unusual muscle pain, tenderness, or weakness, especially if accompanied by fever or malaise. Report these to your doctor immediately as they could indicate muscle injury.
• Diabetes and Hypothyroidism: Patients with diabetes or an underactive thyroid (hypothyroidism) should inform their doctor.
• Lifestyle: Maintain a healthy lifestyle, including a balanced, low-fat diet, regular exercise, smoking cessation, and weight management, to maximize the benefits of the medication.
• Allergies: Do not take Lipicard AV Tablet if you are allergic to atorvastatin, fenofibrate, or any of its ingredients.
• Elderly Patients: Elderly patients should use this medication under medical supervision as they may be more prone to side effects.

What happens if a dose of Lipicard AV Tablet is missed?

If you miss a dose of Lipicard AV Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Lipicard AV Tablet be stored?

Lipicard AV Tablet should be stored in a cool, dry place, ideally below 30°C, away from direct sunlight and moisture. Keep it in its original packaging and ensure it is out of reach of children and pets. The desiccant in the pack helps keep the medicine dry.