Eliwel 75mg Tab

Eliwel 75mg Tablet is a prescription medication manufactured by Sun Pharmaceutical Industries Ltd.. It is a tricyclic antidepressant (TCA) primarily used for its effects on mood and pain signaling.

Name

• Common Name: Amitriptyline
• Brand Name: Eliwel 75mg Tablet

Composition

• Active Ingredient: Amitriptyline 75mg

Uses

Eliwel 75mg Tablet is prescribed for the management and prevention of various medical conditions:

• Major Depressive Disorder: Helps to improve mood and reduce anxiety by balancing certain brain chemicals.
• Neuropathic Pain: Blocks the transmission of pain signals from nerves to the brain, providing relief.
• Migraine: Used for migraine prevention and treatment.
• Chronic Tension-Type Headache: Also effective in treating chronic tension-type headaches.
• Nocturnal Enuresis (Bedwetting): Prescribed to children aged 6 years and above for bedwetting.

Dosage and Administration

Eliwel 75mg Tablet should be taken strictly as advised by a doctor.

• Adults (for Depression): Initial dose is typically 75 mg per day, which can be taken as a single dose at bedtime or in divided doses. The dose may be gradually increased up to 150 mg per day, with maximum doses of 200-300 mg/day for severe depression in hospitalized patients.
• Adults (for Chronic Pain/Migraine Prevention): Initial dose is usually 10-25 mg in the evening. The effective dose is generally 25-75 mg per day.
• Children (for Nocturnal Enuresis): For children 6-10 years old, 10-20 mg per day, 1-1.5 hours before bedtime. For children over 11 years old, 25-50 mg per day, 1-1.5 hours before bedtime. The dose should be increased gradually.
• Administration: Can be taken with or without food, but taking it with food may help avoid stomach problems. It is often recommended to take it before bedtime due to its sedative effects. Tablets should be swallowed whole with water and not chewed, crushed, or broken. Do not stop the medication suddenly without consulting a doctor, as it can lead to withdrawal symptoms. Full therapeutic effects may take several weeks to manifest.

Side Effects

Common side effects may include:

• Drowsiness/sleepiness
• Dry mouth
• Weight gain
• Constipation
• Dizziness
• Headache
• Nausea
• Orthostatic hypotension (sudden drop in blood pressure upon standing)
• Increased heart rate/palpitations
• Blurred vision or accommodation disorders
• Sweating
• Confusion, lack of attention
• Low sex-drive, problems with erection
• Tingling and numbness of arms or legs
• Problems with urination

Serious side effects are rare but include suicidal thoughts, mania, mood changes, hallucinations, and severe liver problems. Seek immediate medical attention if these occur.

Precautions

• Pregnancy: Eliwel 75mg Tablet may be harmful during pregnancy, potentially causing deformations in the baby. It should be used only if clearly necessary and under medical supervision.
• Breastfeeding: The medicine may pass into breast milk and harm the baby; consult a doctor.
• Driving and Operating Machinery: Causes drowsiness, dizziness, and decreased concentration. Avoid driving or operating heavy machinery until you know how it affects you.
• Alcohol: Avoid alcohol consumption as it can increase drowsiness and dizziness and lead to severe side effects.
• Heart Conditions: Not recommended for patients with a recent heart attack, severe heart rhythm issues, or coronary artery disease. Use with caution in patients with other heart problems.
• Liver/Kidney Impairment: Use with caution in patients with kidney disease and is contraindicated in severe liver problems.
• Suicidal Thoughts: Patients, especially those under 18 or with a history of suicidal tendencies, should be monitored closely for suicidal thoughts or mood changes.
• Other Conditions: Exercise caution in patients with epilepsy or seizure disorder, thyroid disorder, bipolar disorder, schizophrenia, narrow-angle glaucoma, enlarged prostate, blockage or stenosis in the gut, diabetes, or imbalances of potassium and magnesium levels.
• Drug Interactions: Inform your doctor about all current medications, including herbal medicines, vitamins, and supplements. Significant interactions can occur with Monoamine Oxidase Inhibitors (MAOIs) (should not be taken within 14 days of Eliwel), blood thinners, anticholinergic medicines, anticonvulsants, anti-anxiety medications, anti-allergics, opioid analgesics, NSAIDs, cimetidine, quinidine, flecainide, disulfuram, cisapride, selegiline, linezolid, artemether, and lumefantrine.

Storage

Store the medicine at room temperature (below 30°C), away from direct heat, moisture, and sunlight. Keep it out of the reach of children. Do not use past the expiry date.

What is Eliwel 75mg Tablet used for?

Eliwel 75mg Tablet, which contains Amitriptyline, is primarily used to treat depression in adults. It is also prescribed for managing neuropathic pain, chronic tension-type headaches, and migraine prevention in adults. Additionally, it can be used to treat bedwetting at night (nocturnal enuresis) in children aged 6 years and above.

How does Eliwel 75mg Tablet work?

Eliwel 75mg Tablet is a tricyclic antidepressant that works by affecting certain chemical messengers in the brain, specifically serotonin and norepinephrine. It increases the levels of these neurotransmitters by preventing their reuptake into nerve cells, which helps to regulate mood, relieve depression symptoms, and reduce the transmission of pain signals.

What is the usual dosage of Eliwel 75mg Tablet?

The dosage of Eliwel 75mg Tablet varies depending on the medical condition and individual response to treatment, and it should always be taken as advised by a doctor. For depression in adults, an initial dose might be 50-75 mg per day, given as a single dose at bedtime or in divided doses, which can be gradually increased up to 150 mg per day. In severe cases, some hospitalized patients may receive higher doses, up to 300 mg per day. For nocturnal enuresis in children aged 6-10 years, the dose is typically 10-20 mg/day at bedtime, and for children aged 11-16 years, it's 25-50 mg/day at bedtime. The tablet can be taken with or without food, usually at a fixed time, often before bedtime due to its drowsiness-inducing effect.

What are the possible side effects of Eliwel 75mg Tablet?

Common side effects of Eliwel 75mg Tablet include sleepiness, drowsiness, dry mouth, constipation, headache, nausea, and weight gain. Other possible side effects can include dizziness, irregular heartbeat, slurred or slow speech, a congested nose, fatigue, confusion, blurred vision, tremors, and orthostatic hypotension (a sudden drop in blood pressure upon standing). Most of these effects are usually mild and resolve over time, but persistent or severe side effects should be reported to a doctor.

Is Eliwel 75mg Tablet safe during pregnancy or breastfeeding?

Eliwel 75mg Tablet is generally not recommended for use during pregnancy unless considered clearly necessary by a physician, as it may be unsafe and has been known to cause deformations in babies in animal studies. If taken during the last trimester, it may cause symptoms in the newborn. It is also probably unsafe during breastfeeding, as the active ingredient (Amitriptyline) can pass into breast milk and potentially harm the baby. Therefore, it is crucial to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can Eliwel 75mg Tablet be taken with other medications?

Eliwel 75mg Tablet can interact with various medications, and it's essential to inform your doctor about all medicines you are taking, including herbal or ayurvedic remedies, vitamins, and supplements. It should not be taken with Monoamine Oxidase Inhibitors (MAOIs) due to the risk of severe side effects, and you should not take Eliwel 75mg Tablet if you have taken MAOIs within the last 14 days. Other medications that may interact include blood thinners, anticholinergic medicines, anticonvulsants, anti-anxiety medicines, anti-allergic medicines, opioid analgesics, NSAIDs, cimetidine, certain heart medicines (like quinidine and flecainide), and thyroid medication.

What precautions should be taken while taking Eliwel 75mg Tablet?

Several precautions should be taken while on Eliwel 75mg Tablet:

• Alcohol Consumption: Avoid consuming alcohol, as it can increase drowsiness, dizziness, and confusion.
• Driving and Machinery: Do not drive or operate heavy machinery if you experience drowsiness, dizziness, or decreased concentration.
• Sudden Blood Pressure Drop: Rise slowly from a sitting or lying position, as the medicine may cause orthostatic hypotension (a sudden drop in blood pressure).
• Suicidal Thoughts: Monitor for sudden mood changes or the development of suicidal thoughts, especially at the beginning of treatment, and inform your doctor immediately.
• Medical Conditions: Exercise caution if you have heart problems (recent heart attack, arrhythmias), liver or kidney disease, diabetes, thyroid disorders, epilepsy/seizure disorder, narrow-angle glaucoma, or an enlarged prostate.
• Abrupt Discontinuation: Do not stop taking the medicine suddenly without consulting your doctor, as it can lead to withdrawal symptoms and worsen your condition. Your doctor may gradually decrease the dose.

What happens if a dose of Eliwel 75mg Tablet is missed?

If you miss a dose of Eliwel 75mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Maintaining a regular dosing schedule is important.

How should Eliwel 75mg Tablet be stored?

Eliwel 75mg Tablet should be stored in a cool, dry place, protected from light, and away from the reach of children. It should typically be stored at room temperature, ideally below 30°C. Do not keep outdated medicine or medicine no longer needed.