Briv + 50 Mg Tablet (10 Tab)

BRIV + 50 MG TABLET

BRIV + 50 MG TABLET, manufactured by Dr. Reddy's Laboratories Ltd., is an anti-epileptic medication designed to manage seizures in individuals with epilepsy.

• Name:
  • Brand Name: BRIV + 50 MG TABLET, BRIV 50 TABLET, Briv 50mg Tablet
  • Common Name: Brivaracetam
• Composition:
  • Each tablet contains 50 mg of Brivaracetam as the active ingredient.
• Uses: BRIV + 50 MG TABLET is primarily used for the treatment of partial-onset seizures in patients with epilepsy. It can be used as a standalone treatment (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) for adults and children aged 1 month and older. This medication helps to stabilize brain activity and prevent the abnormal electrical impulses that lead to seizures, thereby reducing their frequency and severity.
• Dosage and Administration: BRIV + 50 MG TABLET should be taken as prescribed by a healthcare provider.
  • Adults (16 years and older): The recommended starting dose for monotherapy and adjunctive therapy is typically 50 mg twice daily (100 mg/day). The dosage may be adjusted based on clinical response and tolerability, usually not exceeding 100 mg twice daily.
  • Pediatric Patients (1 month to less than 16 years): The dose is dependent on body weight and must be determined by a doctor.
  • The tablet can be taken with or without food.
  • Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet.
  • It is important to take the medication regularly, preferably at the same time each day, for optimal effectiveness. Do not stop taking the medication abruptly, as this can increase the risk of seizures.
• Side Effects: Common side effects may include:
  • Dizziness, fatigue, headache
  • Nausea, vomiting, constipation
  • Mood changes, irritability, anxiety, difficulty sleeping (insomnia)
  • Flu-like symptoms, decreased appetite Serious, though rare, side effects can include suicidal thoughts, severe mood swings, or severe allergic reactions. If any unusual behavioral changes occur, contact a healthcare provider immediately.
• Precautions:
  • Inform your doctor if you have a history of depression, mental health issues, or kidney or liver problems, as dose adjustments may be necessary.
  • Limit alcohol consumption, as it may increase side effects such as drowsiness and dizziness.
  • Do not stop the medication suddenly without consulting your doctor, as this can worsen seizures.
  • Monitor for any new or unusual mood or behavioral changes, including suicidal thoughts, and inform your doctor if they occur.
  • BRIV + 50 MG TABLET may cause drowsiness, tiredness, or dizziness. Avoid driving or operating heavy machinery until you know how the medicine affects you.
  • Inform your doctor about all other medications you are taking, including herbal supplements like St. John's Wort, to avoid potential drug interactions.
  • Consult your doctor if you are pregnant, planning to conceive, or breastfeeding, as its use during pregnancy and breastfeeding should be with caution.
• Storage: Store BRIV + 50 MG TABLET in a cool and dry place below 30°C, away from direct sunlight and moisture, and out of the sight and reach of children.

What is BRIV + 50 MG Tablet used for?

BRIV + 50 MG Tablet, containing Brivaracetam, is an anti-epileptic medication primarily used to control partial-onset seizures in individuals with epilepsy. It can be prescribed for adults and children aged 1 month and older, either alone or in combination with other anti-epileptic drugs, to help reduce the frequency and intensity of seizures.

How does BRIV + 50 MG Tablet work?

Brivaracetam, the active ingredient, works by targeting a specific protein in the brain called synaptic vesicle glycoprotein 2A (SV2A). By binding to this protein, it helps to stabilize the electrical activity of nerve cells and reduce the abnormal electrical impulses that can trigger seizures.

What is the usual dosage of BRIV + 50 MG Tablet?

For adults and adolescents 16 years of age and older, the typical starting dose is 50 mg twice daily (100 mg per day). Your doctor may adjust the dose based on your response and tolerability, with a usual range of 25 mg to 100 mg twice daily (50-200 mg/day). For children aged 1 month to less than 16 years, the dosage is determined by body weight. It is generally taken twice a day, with or without food. Tablets should be swallowed whole and not chewed or crushed. Patients with liver problems may require a lower starting dose and a reduced maximum daily dose.

What are the possible side effects of BRIV + 50 MG Tablet?

Common side effects can include drowsiness, dizziness, fatigue, nausea, vomiting, and constipation. More serious side effects, though less common, can involve changes in mood or behavior such as aggression, anxiety, depression, agitation, or irritability. There is also a small risk of suicidal thoughts or actions. Allergic reactions, characterized by swelling of the face, throat, or difficulty breathing, are also possible. If you experience any severe or persistent side effects, or any concerning mood/behavioral changes, contact your doctor immediately.

Is BRIV + 50 MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: There is limited data on the use of Brivaracetam during pregnancy. Animal studies have indicated a potential for fetal harm. If you are pregnant or planning to become pregnant, discuss this with your doctor. Seizure control is very important during pregnancy, and your doctor will weigh the benefits against the potential risks. Women of childbearing potential should discuss contraception with their healthcare provider.

Breastfeeding: Brivaracetam can pass into breast milk. If you are breastfeeding or plan to breastfeed, consult your doctor. Infants should be monitored closely for any signs of drowsiness, agitation, or changes in weight gain and development. Some healthcare providers may advise against breastfeeding during treatment, while others may recommend increased monitoring of the infant.

Can BRIV + 50 MG Tablet be taken with other medications?

Yes, BRIV + 50 MG Tablet can be used alone or in combination with other anti-epileptic drugs. However, it's crucial to inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications, such as strong enzyme-inducing anti-epileptic drugs (e.g., carbamazepine, phenytoin) or strong enzyme inducers like rifampin or St. John's wort, can affect the levels of brivaracetam or other medications. Taking brivaracetam with other central nervous system (CNS) depressants (like certain opioids or antidepressants) can increase drowsiness and sedation. Always consult your doctor or pharmacist regarding potential drug interactions.

What precautions should be taken while taking BRIV + 50 MG Tablet?

Do not stop taking BRIV + 50 MG Tablet suddenly without consulting your doctor, as this can worsen seizures. The dosage should be gradually reduced under medical supervision. This medicine may cause dizziness, drowsiness, blurred vision, or problems with coordination and balance, so avoid driving or operating heavy machinery until you know how it affects you. Alcohol should be avoided as it can intensify these side effects. It is important to monitor for any changes in mood or behavior, including feelings of depression, anxiety, agitation, aggression, or suicidal thoughts, and report them to your doctor immediately.

What happens if a dose of BRIV + 50 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your healthcare provider for advice.

How should BRIV + 50 MG Tablet be stored?

BRIV + 50 MG Tablet should be stored in a cool, dry place, away from direct sunlight and out of the sight and reach of children. The typical storage temperature is below 30°C (86°F) or between 20°C and 25°C (68°F and 77°F). Do not use the medicine after the expiry date.