Brivazen 25 Mg (10 Tab)

BRIVAZEN 25 MG (10 TAB)

Name:

• Brand Name: BRIVAZEN 25 MG (10 TAB)
• Common Name: Brivaracetam
• Manufacturer: INTAS PHARMACEUTICALS LTD

Composition: Each tablet contains Brivaracetam 25 mg as the active ingredient.

Uses: BRIVAZEN 25 MG is an anti-epileptic medicine prescribed for the treatment of seizures (fits) in epilepsy. It is primarily used for partial-onset seizures and can be administered alone or in combination with other anti-epileptic medications. It works by suppressing abnormal electrical activity in the brain to help prevent seizures.

Dosage and Administration: This medicine should be taken exactly as advised by your doctor. Swallow the tablet whole with a glass of water; do not chew, crush, or break it. It can be taken with or without food, but it is recommended to take it at the same time each day for maximum benefit. The dosage and frequency will be determined by your doctor and may be adjusted gradually. It is generally advised as a long-term treatment, and abrupt discontinuation can worsen seizures.

Side Effects: Common side effects may include:

• Dizziness, headache, drowsiness, fatigue
• Nausea, vomiting, constipation
• Behavioral changes such as agitation, aggressive behavior, irritability, anxiety, depression
• Insomnia, flu-like symptoms, decreased appetite Serious side effects, though rare, can include thoughts of harming oneself. Contact your doctor if your mood changes for the worse.

Precautions:

• Alcohol: Avoid consuming alcohol as it may increase drowsiness and other side effects.
• Pregnancy and Breastfeeding: Consult your doctor. BRIVAZEN 25 MG may be unsafe during pregnancy and is not recommended for breastfeeding mothers as it may pass into breast milk.
• Driving and Operating Machinery: This medicine may cause drowsiness, dizziness, or affect vision. Avoid driving or operating heavy machinery until you understand how it affects you.
• Medical Conditions: Inform your doctor if you have liver or kidney problems, depression, or suicidal thoughts, as dose adjustments or close monitoring may be required. It is not recommended in severe liver problems.
• Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking, especially rifampicin and St. John's wort, to avoid potential interactions.
• Allergy: Do not take if you are allergic to Brivaracetam or any other ingredients in the tablet.
• Children: Not recommended for children under 4 years of age. Approved for use in patients aged 16 years and older for partial-onset seizures as adjunctive therapy.

Storage: Store BRIVAZEN 25 MG tablets in their original packaging at room temperature, ideally below 30°C (20-25°C), away from direct sunlight and moisture. Keep out of the reach and sight of children and pets.

What is BRIVAZEN 25 MG used for?

BRIVAZEN 25 MG is an anti-epileptic medicine primarily used to treat seizures (fits) in individuals with epilepsy. It can be used alone or alongside other medications to help prevent various types of seizures, including partial-onset, myoclonic, and primary generalized tonic-clonic (grand mal) seizures.

How does BRIVAZEN 25 MG work?

BRIVAZEN 25 MG, containing Brivaracetam, works by suppressing the abnormal electrical activity in the brain that causes seizures. It achieves this by binding to specific sites called synaptic vesicle protein 2A (SV2A) on the surfaces of nerve cells, thereby stabilizing neuronal disturbance and preventing the spread of electrical signals that lead to seizures.

What is the usual dosage of BRIVAZEN 25 MG?

The dosage of BRIVAZEN 25 MG is determined by your doctor and may be adjusted based on your response and the severity of your epilepsy. For adults, a common starting dose is 50 mg twice daily. The tablet should be swallowed whole with water and can be taken with or without food, ideally at the same time each day to maintain consistent levels in your body.

What are the possible side effects of BRIVAZEN 25 MG?

Common side effects include dizziness, headache, nausea, vomiting, drowsiness, and fatigue. You might also experience behavioral changes such as agitation, aggressive behavior, irritability, anxiety, or insomnia. In some cases, there can be serious side effects like thoughts of harming oneself. If any side effects persist or worsen, or if you experience significant mood changes, contact your doctor.

Is BRIVAZEN 25 MG safe during pregnancy or breastfeeding?

BRIVAZEN 25 MG may be unsafe to use during pregnancy, as animal studies have shown harmful effects on the developing baby. It is not known if Brivaracetam passes into breast milk. Therefore, it is generally not recommended during breastfeeding, and you should consult your doctor to weigh the potential benefits against the risks.

Can BRIVAZEN 25 MG be taken with other medications?

BRIVAZEN 25 MG can be used as an add-on therapy with other anti-epileptic drugs. However, it's important to inform your doctor about all medications, supplements, or herbal products you are taking to avoid potential interactions. For example, it may interact with rifampicin, St. John's wort, carbamazepine (increasing its active metabolite), phenytoin (requiring monitoring of levels), and other CNS depressants which could enhance drowsiness.

What precautions should be taken while taking BRIVAZEN 25 MG?

Do not stop taking BRIVAZEN 25 MG abruptly without consulting your doctor, as this can worsen your seizures. This medicine may cause drowsiness, dizziness, or problems with balance and coordination, so avoid driving or operating heavy machinery until you know how it affects you. It is also advisable to avoid alcohol consumption as it may increase drowsiness and calmness. Inform your doctor if you have liver or kidney problems, depression, or suicidal thoughts, as these conditions may require dose adjustments or close monitoring.

What happens if a dose of BRIVAZEN 25 MG is missed?

If you miss a dose of BRIVAZEN 25 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this may increase the chances of side effects.

How should BRIVAZEN 25 MG be stored?

BRIVAZEN 25 MG should be stored at room temperature, generally below 30°C. Keep it in a dry place, away from direct sunlight and moisture, and in its original packaging. Ensure it is kept out of the sight and reach of children and pets. Do not use the medicine after its expiry date.